抽动秽语综合征的临床诊断治疗分析  

Clinical Diagnosis and Treatment of Tourette's Syndrome

作　　者：侯晓利[1] 宋涛[1] 王真[1] 

机构地区：[1]大连大学附属中山医院儿科,辽宁省大连市116001

出　　处：《中华全科医学》2011年第2期191-191,332,共2页Chinese Journal of General Practice

摘　　要：目的探讨抽动秽语综合征的临床诊断和治疗效果。方法对2008年4月-2009年6月在儿科门诊就诊的60例抽动秽语综合征患儿做脑电图及实验室相关检查,用小剂量氟哌啶醇治疗,治疗4周进行疗效判定,随访时间至12个月。结果脑电图异常25例(41.7%),其中轻度异常18例,中度异常7例,无特异性波形;小剂量氟哌啶醇治疗显效率73.3%,总有效率96.7%,不同疗效组治疗后进步率之间差异具有统计学意义(P<0.01)。结论脑电图对抽动秽语综合征的临床诊断及疗效判定有一定帮助;小剂量氟哌啶醇治疗本病有较好效果,与安坦合用,可以减少此药的毒副作用,不良反应少。药物治疗的同时,还应重视心理或生理因素,加强支持性心理治疗,使患儿正常成长。Objective To investigate the clinical diagnosis and treatment of Tourette＇ s syndrome. Methods From April 2008 to June 2009, EEG and laboratory tests were performed in 60 cases of outpatients with Tourette＇ s syndrome, and a small dose of haloperidol as administrated. The therapy efficacy was evaluated after the treatment of 4 weeks. The follow-up was 12 months. Resuits Twenty cases were with abnormal EEG（ 18 was mild and 7 was severe） ,no specific wave was found. The obvious effective rate of a small dose of haloperidol treatment was 73.3% ,and the total effective rate was 96.7%. The difference of therapy efficiency before and after the treatment had statistical significance in every groups（ P 〈 0.01 ）. Conclusion EEG is helpful for the diagnosis of Tourette＇ s syndrome. A small dose of haloperidol is effective for the disease, and the combination of Artane can reduce the toxic and side effect. The supportive psychotherapy should also be paid more attentions in order to make children grow properly.

关 键 词：抽动秽语综合征 氟哌啶醇 

分 类 号：R749.94[医药卫生—神经病学与精神病学]