缺血性脑血管病二级预防阿司匹林药物应用状况调查  

The Cross-section Study on the Status of Aspirin Application in Secondary Prevention of Cerebral Ischemic

作　　者：胥丽霞[1] 孟秀君[1] 侯率[1] 费学萍[1] 康志伟[1] 高素兰[1] 徐瑞珍 孙美波 宋晓 杨岗 吴敬湘 王秀清 

机构地区：[1]中国医科大学附属第四医院神经内科,沈阳110005 [2]辽宁省大洼县医院内科,辽宁大洼124200 [3]辽宁省庄河市人民医院内科,辽宁庄河116400 [4]辽宁省本溪县一院内科,辽宁本溪117100 [5]辽宁省西丰县第一医院内科,辽宁西丰112400 [6]辽宁省建平县医院内科,辽宁建平122400 [7]辽宁省阜新县人民医院内科,辽宁阜新123100

出　　处：《中国医科大学学报》2010年第12期1033-1036,共4页Journal of China Medical University

基　　金：国家"十一五"科技攻关计划项目(2007BAI07A13)

摘　　要：目的了解辽宁省农村地区缺血性脑血管病二级预防阿司匹林药物应用现状,为改进缺血性脑血管病二级预防工作提供依据。方法本研究为现况调查,由乡村医生对辽宁省本溪县、西丰县、阜新县、建平县、大洼县、庄河市6个县市141个乡镇的4274例缺血性脑血管病患者进行面对面的问卷调查,调查患者的基本信息及应用阿司匹林的状况,根据阿司匹林应用情况将患者分为规律服药组、不规律服药组和未服药组,并对缺血性脑血管病患者进行二级预防知识讲座、实施规范化管理,3个月后随访比较管理前、后上述患者的阿司匹林应用状况。结果 3个组管理前、后阿司匹林的应用率分别是34.44%和60.57%(规律服药组)、55.76%和30.22%(不规律服药组)、9.80%和9.17%(未服药组);男性、年收入低、脑血管病亚型及神经功能预后(MRS评分)是影响阿司匹林应用率的重要因素。结论辽宁省农村地区缺血性脑血管病患者阿司匹林应用率低,性别、脑血管病亚型、经济水平及神经功能预后显著影响阿司匹林的应用率,在农村进行缺血性脑血病二级预防的规范化管理可以提高阿司匹林应用率,建立一套完整的脑血管病防治管理体系非常必要。Objective To investigate the application status of aspirin in the secondary prevention of cerebral ischemic in Liaoning province and to provide the clues for improving the secondary prevention.Methods The study was a cross-sectional investigation.4 724 patients with the diagnosis of cerebral ischemic from 141 towns of 6 counties in Liaoning province including Benxi,Xifeng,Fuxin,Jianping,Dawa and Zhuanghe.The data of personal details and application status of aspirin were collected through face-to-face questionnaire by rural doctors.According to the administration of aspirin,the patients were classified into three groups：regular medication group,irregular medication group,and non-medication group,then all patients were granted to teach the lecture of secondary prevention and managed standard.After 3-month followup,the application status of aspirin was investigated to compare with that before management.Results The application proportion of aspirin before and after management in the three groups were 34.44% and 60.57%,55.76% and 30.22%,9.80% and 9.17% respectively;male,low annual income,subtype of cerebral ischemic and MRS scores were important factors for the application of aspirin.Conclusion The application proportion of aspirin in towns of Liaoning province was low.There were several significant factors that affected the application proportion of aspirin including sex,economic level,subtype of cerebral ischemic and MRS scores.Implementing standardization management of cerebral ischemic in secondary prevention could improve the applications proportion of aspirin,so it is very important to establish a complete system.

关 键 词：缺血性脑血管病 阿司匹林药物应用 二级预防 

分 类 号：R743.4[医药卫生—神经病学与精神病学]