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作 者:赵连爽[1] 赵俊华[2] 赵玉霞[3] 门桐林[4] 曹丽艳[2] 范增慧[2]
机构地区:[1]中国医科大学附属第一医院柃验科,沈阳110001 [2]中国医科大学94期临床医学7年制,沈阳110001 [3]中国医科大学附属第一医院肿瘤放射治疗科,沈阳110001 [4]沈阳市胸科医院肿瘤二科,沈阳110044
出 处:《中国医科大学学报》2010年第12期1048-1050,共3页Journal of China Medical University
基 金:沈阳市社会事业科技创新项目资助(1081269-9-00)
摘 要:目的探讨肺癌患者临床病理资料,为临床的诊治工作提供科学理论依据。方法对经手术切除的568例肺癌患者的临床资料、病理类型和部位进行统计分析。结果在568例中男∶女为2.17∶1(389/179),周边型肺癌∶中心型肺癌为1.35∶1(326/242),发生在右肺上中下叶的分别为26.2%、7.9%和24.5%,左肺上、下叶分别为22.5%和18.9%,右肺多于左肺,上肺叶多于下肺叶;肺鳞癌为36.1%、肺腺癌为50.4%,肺小细胞癌为7.0%、其他类型肺癌占6.5%;在女性患者中腺癌占71.5%、男性患者中鳞癌为45.0%。男女病理类型构成有明显的统计学差异(P<0.01)。吸烟者326例(57.4%),不吸烟者242例(42.6%)。在肺鳞癌、肺腺癌及小细胞肺癌中,吸烟者分别占71.2%、45.1%和65.0%,各组间差异有统计学意义(P<0.01)。结论在手术切除的肺癌患者中以男性、周边型为多,肺腺癌处于所有病理类型的首位,吸烟者易患肺鳞癌,以中心型肺癌为多。Objective Investigate the clinical pathological data of 568 patients with lung cancers in order to provide scientific basis for clinical diagnosis and treatment.Methods The statistical analysis was used to analyze the clinical data,pathological types and tumor locations of 568 lung cancer patients undergoing surgery.Results Among the 568 patients,the ratio of male to female was 2.17:1(389/179),and the ratio of peripheral lung cancer to central lung cancer was 1.35:1(326/242).The incidence that tumor located in right upper,middle,and lower lobe of lung cancer was 26.2%,7.9%and 24.5% respectively,while that in left upper and lower lobe was 22.5 % and 18.9%.The incidence of lung cancer in right side was higher than left side,and higher in the upper lobe than lower lobe.Lung squamous cell carcinoma accounted for 36.1%,Adenocarcinoma 50.4%,SCLC7.0%,and others 6.5% among the whole types.The adenocarcinoma accounted for 71.5% in female patients,while the squamous cell carcinoma accounted for 45.0% in male patients.There was a statistically significant difference(P 〈 0.01)in pathological types between males and females.There were 326(57.4%)smokers and 242(42.6%)non-smokers.Smokers accounted for 71.2 %,45.1% and 65% respectively in squamous cell carcinoma,lung adenocarcinoma and small cell lung cancer with statistically difference among groups(P 〈 0.01).Conclusion It seems that lung cancer appears more frequently in males with peripheral carcinoma in exairesis.Lung adenocarcinoma is the most among the whole pathological types.Smoking patients are more likely to get squamous cell carcinoma,with central lung cancer appearing more frequently.
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