不均等分割放射治疗口腔癌的临床研究  

Reseaech on Irregular Fractionated Irradiation of Mouth Cavity Cancer

作　　者：万志龙[1] 马煌如[1] 何晓军[1] 赵季忠[1] 刘向阳[1] 顾红芳[1] 

机构地区：[1]江苏南通市肿瘤医院放疗科,226361

出　　处：《肿瘤防治研究》1999年第6期467-468,共2页Cancer Research on Prevention and Treatment

摘　　要：1986年1月至1993年12月，102例口腔部进行放射治疗，其中不均等分割51例。剂量分布：6Gy（A）→1．2Gy（B）→1．2Gy（A）→1．2GY（B）→1．2GY（A），休息二天后再重复。总肿瘤量64．8Gy/6W（10．8Gy／W×6）。同期对照组51例均等分割放疗，总肿瘤量66Gy／6．5W（10Gy／W×6．5）。结果近期疗效，不均等分割组为96．1％，均等分割组为74．5％；5年生存率不均等分割组为43．1％，均等分割组为21．6％。因此，两组有显著性差异（P＜0．05）。From 1986 to 1993, 102 mouth cavity caricinoma patients were botecl by radiotneraPy, of them, 51 were given irregular tractionated irradiation. They received 6Gy (A)→1 .2Gy (B)→1.2Gy (A)→1.2GY (B)→1.2GY (A). Afer a rest of two days, the forve cgcle was repeated. The total dose given was 64.8Gy/6W (10.8Gy/W × 6). 51 patients treated by conventional fmehonahon irradiation. The total dose given was 66Gy/6. 5W (10Gy/W×6. 5). Resulto: The improvement rate of short-term carative effect was 96. 1 % in the irregular tructionation irradiation graup, and 74. 5 % in thd conventional fraup Five-Year survival rate was 43. 1% in the irregular tractionation idrieation group, and 21 .6% in the conventional one, with a remarkably difference between them (P＜0.05)

关 键 词：口腔癌 放射疗法 不均等分割 临床研究 

分 类 号：R739.805[医药卫生—肿瘤]