高亲水性软接触镜材料的研究  

Studies on soft Contact lens materials with high Water content

作　　者：李沁华[1] 邹翰[1] 

机构地区：[1]暨南大学生物医学工程研究所,广东广州510632

出　　处：《暨南大学学报（自然科学与医学版）》1999年第3期100-104,共5页Journal of Jinan University(Natural Science & Medicine Edition)

摘　　要：研制出高亲水性的软接触镜材料，其主要组分为甲基丙烯酸β－羟乙酯（ＨＥＭＡ）和Ｎ－乙烯基吡咯烷酮（ＮＶＰ），用安息香为引发剂，紫外高压汞灯为光源，通过光引发自由基聚合反应，探讨了聚合过程中ＨＥＭＡ与ＮＶＰ的用量配比和添加剂甲基丙烯酸酯类用量对材料含水率的影响实验结果最佳配比为：ＮＶＰ用量为６０％，光引发剂安息香用量为０．２％，添加剂甲基丙烯酸酯类用量为１０％红外光谱和紫外光谱定性说明了聚合反应完全，扫描电镜显示出材料组织形态是均匀的网孔状，材料的性能指标达到使用要求材料含水率为７８％，透光率为９５％，抗张强度为３２８．５０Ｐａ（湿态下）Soft contact lens materials were obtained from HEMA and NVP Polymerization reaction.Uvtraviolot light was used as light source and storax as light sensibility agent. The effects of HEMA, NVPand methacrylate compostion in polymeric system were investigated. IR and UV spectra were used to determine polymeric system were investigated. IR and UV spectra were used to determine polymerizablemonomer conversion in reaction. Polymer network morphology was investigated by SEM. The optimumcomposition by weight for contact lens materials was 60% NVP, 0. 2% storax and 10% methacrylate.The contact lens made of HEMA - NVP has a water content of 78%, transissivity at least 95% and tensile strength 328 .50 Pa (in water). Unreacted monomer concentrantion was very low.

关 键 词：软接触镜 含水率 亲水性 水凝胶 HEMA NVP 

分 类 号：TS959.7[轻工技术与工程] R318.08[医药卫生—生物医学工程]