三维超声造影增强显像在消化系统肿瘤诊断中的应用  

Application of three-dimensional contrast-enhanced ultrasonography in diagnosis of digestive system tumors

作　　者：施红[1] 余秀华[1] 张宏[1] 钱斌[1] 卫张蕊[1] 汪贤臣[1] 孔梓祥[1] 徐建平[1] 郭心璋 李黎[1] 

机构地区：[1]解放军第117医院超声科,杭州310013 [2]浙江遂昌人民医院超声科

出　　处：《中华临床医师杂志（电子版）》2011年第1期87-90,共4页Chinese Journal of Clinicians(Electronic Edition)

基　　金：南京军区医学科技创新基金重点资助项目(09Z039)

摘　　要：目的探讨三维超声造影增强显像(3D CEUS)技术在消化系统肿瘤诊断中的应用价值。方法经手术病理或CT印证的消化系统肿瘤81例,分成良性病灶组和恶性病灶组。静脉注射超声造影剂SonoVue,应用低机械指数造影方法,在二维超声造影增强显像(2D CEUS)的基础上进行3D CEUS。描记二维造影的时间-强度曲线,将三维造影显像特征进行评分,计算3D CEUS对恶性病灶诊断的敏感性、特异性和预期准确性。结果 3D CEUS可显示病灶整体的立体影像、结构层次和血管空间分布,较2D CEUS更为形象,并可从不同角度观察恶性肿瘤的血管特征。应用3D CEUS特征评分,得出对本组消化系统恶性病灶诊断的敏感性、特异性和预期准确性分别为97.7%、94.7%和95.5%。结论 3D CEUS使超声图像的显像质量得到新的提高,为消化系统肿瘤的临床诊断提供了更多的补充信息。Objective To investigate the value of three-dimensional contrast-enhanced ultrasonography （3D CEUS） in the diagnosis of digestive system tumors.Methods 81 digestive system tumor patients,which were verified by pathology or CT,were divided into benign and malignant groups.Ultrasound contrast agent SonoVue was delivered by intravenous injection and the low mechanic index was used.3D CEUS was practiced on the basis of two-dimensional（2D） CEUS.Time-Intensity curves of 2D CEUS was traced and 3D CEUS imaging characteristic was scored,then the sensitivity,specificity and expected accuracy of 3D CEUS to malignant tumor was calculated.Results 3D CEUS could display the integrated stereoscopic image,structure order and angio-spatial distribution of tumor,which was more visualized than 2D CEUS,and could view the angio-characteristic of malignant tumor from hetero-views.The sensitivity,specificity and expected accuracy of 3D CEUS to digestive system malignant tumors were 97.7%,94.7% and 95.5%,respectively.Conclusions 3D CEUS may improve the imaging quality and provide more supplementary information for the clinical diagnosis of digestive system tumors.

关 键 词：消化系统肿瘤 造影剂 成像 三维 超声检查 

分 类 号：R735[医药卫生—肿瘤]