急性闭塞性脑血管病的动脉溶栓治疗(附21例报告)  

Intra arterial thrombolytic therapy of acute occlusive cerebral vascular disease.

作　　者：陆进[1] 余准[1] 蒋兆贯[1] 徐淦泉[1] 

机构地区：[1]江苏省无锡市第一人民医院

出　　处：《介入放射学杂志》1999年第1期3-5,共3页Journal of Interventional Radiology

摘　　要：目的探讨经脑动脉内注溶栓药物治疗急性闭塞性脑血管病的临床效果。材料与方法本组２１例。起病至溶栓治疗时间３～２０小时。采用微导管技术将导管超选至靶血管闭塞点或闭塞血管起始段。尿激酶用量不超过１００万单位，灌注溶栓时间最大不超过２小时。结果灌注溶栓治疗后脑血管造影复查，闭塞时间６小时内的９例中，完全再通７例。闭塞时间超过６小时的１２例，完全再通６例。总计治愈８例，显效５例，有效４例，无效４例，其中１例死亡。结论动脉内灌注溶栓药物治疗急性闭塞性脑血管病效果满意。Objective To evaluate the value of intra arterial thrombolytic therapy in the treatment of acute occlusive cerebral disease. Methods We analysed 21 cases included 14 males and 7 females, mean age was 63.9 years old. The time from onset to the treatment was 3～20 hours, 9 cases were treated within 6 hours, and 12 cases were more than 6 hours. With microcatheter technique, we set the catheter to the occlusive spot or the beginning of the occlusive vessel. The dose of UK was less than 1 000 000U, and the time of perfusion was shorter than 2 hours. Results Follow up cerebral angiography of 9 cases treated within 6 hours showed complete patency in 7 cases and partial patency in 1 case. Other 12 patients whose treatment started beyond 6 hours outcame with complete patency in 6 and partial patency in 2. 8 cases were cured, 9 cases were improved, 4 cases were effectiveless including a on fatal.Conclusions the effectives of intra arterial thrombolytic therapy was satisfied. The efficacy of patients treated within 6 hours was better than over 6 hours. Secondary hemorrhage could be controlled by clinical treatment.

关 键 词：脑血管闭塞 溶栓治疗 急性 

分 类 号：R743.320.5[医药卫生—神经病学与精神病学]