正交试验优选复方叶下珠的水提制备工艺  

Optimal Water-Extraction of compound phyllanthus urinaria by Orthogonal Design

作　　者：徐晓梅[1] 谭本仁[1] 刘贤英 许卫关[1] 

机构地区：[1]汕头大学医学院附属粤北人民医院,512026 [2]顺德顺风药业有限公司,528300

出　　处：《首都医药》2011年第4期55-56,共2页Capital Medicine

摘　　要：目的优选复方叶下珠的最佳水提工艺。方法采用正交试验,以没食子酸为考察指标对影响复方叶下珠水提工艺的因素进行研究。结果煎煮时间,加水量,醇沉浓度对考察指标具有显著性差异。优选复方叶下珠的水提工艺为:加水10倍,煎煮1小时,醇沉浓度:60%。结论该提取工艺稳定可行,对有效成分的提取较完全。Objective To optimize chose the water extraction of compound phyllanthus urinaria. Methods Using gallate to the indexes by the orthogonal test,study the factor of affecting the water extraction of compound phyllanthus urinaria.Results Boiling time,the amount of water and the concentration of alcohol precipitation have significant differences in the indexes. The optimizing chosen water extraction of compound phyllanthus urinaria：10 times amount of the water,the time of decoction was totally 1 hours,the concentration of alcohol precipitation was 60%. Conclusion The extraction technology is stable and feasible,for more complete in the extraction of effective components.

关 键 词：复方叶下珠 没食子酸 正交试验 水提醇沉 

分 类 号：R259.75[医药卫生—中西医结合]