松果体对大鼠体温节律调节的研究  

A study on regulation of temperature rhythm in rat pineal

作　　者：秦立强 童建[1,2] 

机构地区：[1]江苏省盐城市卫生防疫站 [2]苏州医学院

出　　处：《中国行为医学科学》1999年第2期91-92,共2页Chinese Journal of Behavioral Medical Science

基　　金：国家自然科学资金

摘　　要：目的探讨大鼠体温调节的中枢机制。方法通过毁损ＳＣＮ和松果体以及在松果体中注入ＭＴＸ，观察大鼠一天中体温的变化规律。结果毁损ＳＣＮ后不影响大鼠的体温和昼夜节律性。毁损松果体以及在松果体中注入ＭＴＸ后，大鼠的体温明显下降，并且昼夜节律性也消失。结论松果体通过ＭＴ调节大鼠的体温节律。Objective To study the system of temperature regulation in rat. Methods We observed the rat temperature rhythm in one day when SCN or pineal was injured or MTX was injected to pineal. Results The rat temperature and circadian wasn't affected when SCN was injured. But rat temperature declined and circadian died out when pineal was injured and MT was injected to pineal. Conclusion The pineal regulate rat temperature by melatonin.

关 键 词：松果体 视交叉上核 褪黑素 昼夜节律 体温 

分 类 号：Q426[生物学—神经生物学]