血浆置换术在浆细胞病中的应用  

Clinical application of plasma exchange in treating plasma cell dyscrasis

作　　者：裴晓玲[1] 张金巧[1] 刘改芳[1] 

机构地区：[1]河北医科大学第三医院,050021

出　　处：《中国肿瘤临床与康复》1999年第4期63-63,62,共2页Chinese Journal of Clinical Oncology and Rehabilitation

摘　　要：目的　研究血浆置换术在浆细胞病中的应用价值。方法　用ＡｕｔｏｐｈｅｒｅｓｉｓＣｐｌａｓｍ ａｐｈｏｒｅｓｉｓ ｓｙｓｔｅｍ Ａ２００型　自动血浆分离器对９例浆细胞病进行血浆置换（ＰＥ）疗法，其中多发性骨髓瘤（ＭＭ）９例，巨球蛋白血症（ＭＰ）３ 例。结果　６例多发性骨髓瘤和３例巨球蛋白血症病人经过血浆置换后临床症状明显改善，免疫球蛋白指标显著下降。结论　ＰＥ可清除血浆中异常球蛋白，改善高血液粘滞状态，是目前对浆细胞病的重要治疗手段和方法。? Objective To study the curative effect of plasma exchange (PE) on treating plasma cell dyscrasis.Methods Plasma exchange (PE) was performed in nine plasma cell dycrasis patients (6 multiple myloma patients and 3 macroglobulinemia patients)by Autopheresis C plasmapheresis system (Model A 200).Results The symptoms of all nine patients were improved obviously and the laboratory indexes such as immunoglobin decreased markedly after PE.Conclusions Plasma exhange has the effect of clearing plasma abnormal immunoglobin,alleviating hyperviscosity state and is an important therapy for treating plasma cell dyscrasis. 〔

关 键 词：血浆置换 浆细胞病 

分 类 号：R733.305[医药卫生—肿瘤] R553.05[医药卫生—临床医学]