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作 者:郭伟[1] 张忠涛[1] 刘洋[1] 韩威[1] 金岚[1] 李建设[1] 王宇[1]
机构地区:[1]首都医科大学附属北京友谊医院普外科,北京100050
出 处:《中华普外科手术学杂志(电子版)》2011年第1期29-31,共3页Chinese Journal of Operative Procedures of General Surgery(Electronic Edition)
基 金:国家自然科学基金(30700796);国家十一五科技支撑项目(2006BAI02A13);北京市科技新星计划(2008A086)资助
摘 要:目的探讨胰体尾癌的临床特点、外科手术治疗方法及预后相关因素。方法回顾性分析1996年至2009年行手术探查并获得随访的93例胰体尾癌病例的临床病理资料。结果 93例胰体尾癌患者手术探查病例中,80例患者(86.0%)获得根治,8例患者姑息切除,5例患者单纯探查。中位生存时间(16±0.56)个月。其1、2、3年生存率分别为(69.9±4.8)%、(19.4±4.1)%和(8.6±2.9)%。手术方式、淋巴结转移、肿瘤TNM分期和分化程度与患者的生存时间相关。结论胰体尾癌的预后受多种因素的影响,改善胰腺癌的疗效需要综合治疗水平的提高。Objective To explore the clinical characteristics,surgical treatment and relative factors affecting the prognosis of adenocarcinoma of the body and tail of the pancreas.Methods The clinical data of 93 cases of adenocarcinoma of the tail and body of the pancreas who had undergone operation were reviewed and relative factors influencing the prognosis were analyzed.Results Eighty cases(86.0%) underwent radical resection,and 8 palliative resections,and 5 explorations.The overall median survival time was(16±0.56) months,and the 1-,2-,3-year survival rate was(69.9±4.8)%,(19.4±4.1)% and(8.6±2.9)% respectively.Surgical procedure,lymph node metastasis,TNM staging and tumor differentiation were significantly related to the prognosis of the cases.Conclusions The prognosis of adenocarcinoma of the body and tail of the pancreas was influenced by multiple factors,and the improvement of therapeutic effect should be dependent on integrated treatment.
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