罗哌卡因与左旋布比卡因治疗乳腺癌根治术后创面积液的效果比较  

A Clinical Research on the Effect of Levobupivacaine and Roplvacaine in Curing Seroma after Modified Radical Mastectomy

作　　者：刘殿臣[1] 张冰[1] 蔡海峰[1] 

机构地区：[1]唐山市人民医院麻醉科,河北省唐山063000

出　　处：《中国基层医药》2011年第1期35-36,共2页Chinese Journal of Primary Medicine and Pharmacy

摘　　要：目的 比较盐酸罗哌卡因与左旋布比卡因在乳癌根治术后创面积液治疗中的临床疗效.方法 选择经乳腺癌改良根治术治疗后仍有引流管液量的患者,随机分为左旋布比卡因组（L组）30例,罗哌卡因组（R组）30例,另选择不予星状神经节阻滞者为对照组（C组）30例,记录开始治疗前和治疗第7天、第10天当天的引流液量、创面愈合情况、拔除引流管例数.结果 与C组比较,L与R组积液量均减少（t=4.401、4.470,均P＜0.05）,拔管例数增多.R、L、C三组治愈率分别为76.7%、73.3%、20.0%.结论 盐酸罗哌卡因与左旋布比卡因在星状神经节阻滞治疗乳癌根治术后创面积液治疗中的临床疗效均安全可靠,二者均可应用于星状神经节阻滞治疗乳癌根治术后创面积液.Objective To observe therapeutic effect of levobupivacaine and roplvacaine in curing seroma after modified radical mastectomy of breast cancer by satellite ganglion block. Methods A total of 90 patients were collected and randomly divided into three groups. L group （Levobupivacaine） included 30 patients. 30 patients were in R group（roplvacaine）. The rest 30 patients in the control group were treated without satellite ganglion block. The amount of drainage, the condition of incision concrescence, the number of drainage tube pulled out before the treatment as well as on the seventh day and tenth day after the treatment were recorded respectively. Results Statistical significance was found between C group and L, R group in prior and post treatment, the amount of seroma decreased on each observation point （P 〈 0.05）, the number of drainage tube pulled out increased （ P 〈 0.05 ）. No significant differences were found between L and R group （ P 〉 0.05）. Conclusion The application of levobupivacaine and roplvacaine in curing seroma after modified radical mastectomy of breast cancer by satellite ganglion block was safe and effective, both of them could be used.

关 键 词：罗哌卡因 左旋布比卡因 星状神经节阻滞 乳腺肿瘤 

分 类 号：R737[医药卫生—肿瘤] R61[医药卫生—临床医学]