胃肠道肿瘤干细胞的研究进展  

Advances in Study of Gastrointestinal Cancer Stem Cells

作　　者：许琦[1,2] 冉志华[2] 

机构地区：[1]上海交通大学医学院附属仁济医院肿瘤科,200127 [2]上海交通大学医学院附属仁济医院消化内科上海市消化疾病研究所

出　　处：《胃肠病学》2011年第1期45-47,共3页Chinese Journal of Gastroenterology

摘　　要：近年,肿瘤干细胞作为肿瘤发生、发展的新理论正受到越来越多的关注。在多种肿瘤组织中发现和分离出肿瘤干细胞为证实肿瘤干细胞的存在和干细胞相关特性提供了理论依据。近期研究发现部分胃肠道肿瘤细胞具有干细胞特性,是胃肠道肿瘤发生、发展、逃避常规抗肿瘤治疗的重要原因,为胃肠道肿瘤的治疗提供了新的靶点。本文就肿瘤干细胞,特别是胃肠道肿瘤干细胞的研究进展作一综述。As a new theory for cancer genesis and development, more and more attention has been paid to cancer stem cells in recent years. Discovery and isolation of cancer stem cells from many cancers theoretically certified their existence and characteristics. Recent studies have demonstrated that part of the gastrointestinal cancer cells hold the property of stem cells, which may explain the genesis and development of gastrointestinal cancers and their escaping from routine anticancer therapy. Study in this field provides a new target for gastrointestinal cancer therapy. This article reviewed the advances in study of cancer stem cells, especially gastrointestinal cancer stem cells.

关 键 词：胃肠肿瘤 肿瘤干细胞 肿瘤标记 生物学 分子作用机制 

分 类 号：R735[医药卫生—肿瘤]