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作 者:何悦[1] 庄乾伟[1] 田臻[2] 张春叶[2] 杨伟玲
机构地区:[1]上海交通大学医学院附属第九人民医院.口腔医学院口腔颌面外科,上海200011 [2]上海交通大学医学院附属第九人民医院.口腔医学院口腔病理科上海市口腔医学重点实验室,上海200011 [3]山东省诸城市人民医院口腔科,山东诸城262200
出 处:《中国口腔颌面外科杂志》2011年第1期31-35,共5页China Journal of Oral and Maxillofacial Surgery
基 金:国家自然科学基金(30973341/C170802);上海市科学技术委员会资助项目(08DZ2271100);上海市重点学科建设项目(S30206)~~
摘 要:目的:评价经下颌切迹入路的细针穿吸细胞学检查(FNAC)在面侧深部肿物诊断中的应用价值。方法:应用细针穿吸方法,对40例面侧深部肿物患者进行细胞学检查。男24例,女16例;年龄3~75岁,平均年龄43.28岁。将细胞学检查结果与术后组织病理学检查结果或随访资料进行比较,计算FNAC诊断准确率及在区别肿瘤与非肿瘤、恶性肿瘤与良性病变上的敏感度和特异度。结果:FNAC诊断准确率为80.00%;诊断肿瘤与非肿瘤的敏感度为80.77%,特异度为100.00%,5例患者为假阴性,假阴性率为19.23%,假阳性率为0;诊断恶性肿瘤与良性病变的敏感度为80.00%,特异度为88.00%。3例患者为假阴性,假阴性率为20.00%,3例患者为假阳性,假阳性率为12.00%。结论:FNAC是一种安全性好,操作简单,患者易于接受的诊断方法,在不易做切除及切取活检的面侧深部肿物的定性诊断中有较高的准确率,能准确区别肿瘤与非肿瘤、恶性肿瘤与良性病变,为临床治疗提供依据。PURPOSE:To evaluate the effectiveness of FNAC as a diagnostic tool for lesions in the deep region of lateral face in the route of sigmoid notch.METHODS:FNAC results of 40 cases with lesions in the deep region of lateral face were compared with the final pathologic diagnosis or conditions of follow-up,then the data were used to calculate the diagnostic accuracy of FNAC and the sensitivity and specificity for distinguishing neoplasms from non-neoplasms and malignant tumors from benign lesions.RESULTS:The accuracy of FNAC was 80.00%,the calculated sensitivity,specificity and false-negative rate of FNAC in diagnosis of tumors were 80.77%,100.00%,and 19.23%;and 80.00%,88.00%,20.00% in diagnosis of malignant tumors or benign lesions,respectively.CONCLUSION:FNAC is a safe,simple and accurate tool for establishing the diagnosis of lesions in the deep region of lateral face and can contribute to make therapeutic strategy,such as operation or anti-inflammatory therapy,in many patients by confirming tumors and malignant neoplasms.
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