磁敏感成像技术在肝脏局灶性病变的初步应用  

Clinic application of susceptibility weighted imaging in the discovery and diagnosis of focal liver lesions

作　　者：李秋云[1] 肖恩华[1] 李华兵[1] 卞读军[1] 贺忠[1] 

机构地区：[1]中南大学湘雅二医院放射科,湖南长沙410011

出　　处：《中国临床医学影像杂志》2011年第2期100-104,共5页Journal of China Clinic Medical Imaging

基　　金：十一五国家科技计划项目(2007BAI05B06);国家自然科学基金(30070235;30470508;30870695);湖南省自然科学基金重点项目(06JJ20081);湖南省自然科学基金项目(07JJ6040);长沙市科技计划重点项目(K071532-11)

摘　　要：目的:探讨磁敏感加权成像(SWI)在肝脏局灶性病变内部结构的显示能力及其鉴别诊断中的应用价值。方法:搜集18例经临床及影像证实肝脏病变包括血管畸形、肝细胞癌、转移瘤、血管瘤以及肝囊肿患者共25个肝局灶性病变行常规T1WI、T2WI及SWI扫描,并将其SWI图像与常规MRI序列进行比较。18例均同时行增强扫描,1例动静脉畸形同时行MRA检查,1例血管瘤动态增强后再次行SWI检查。结果:1例血管畸形SWI能较常规平扫、增强及3D MRA更清楚显示其异常静脉血管形态;4例肝细胞癌、3例胆管细胞癌及2例转移瘤,SWI均能显示病灶内瘤静脉及血液降解产物;5例肝血管瘤及3例肝囊肿,SWI均显示病灶呈均匀稍高信号,病灶较大者邻近静脉受压。结论:SWI在显示肝脏静脉性血管畸形、肿瘤相关静脉结构等方面优于常规MR序列,对肝脏局灶性病变有一定鉴别诊断价值,是研究肝脏局灶性病变内部结构的一种新的方法。Objective： To investigate the value of susceptibility weighted imaging in the discovery and diagnosis of focal liver lesions.Methods： Eighteen patients with 25 focal liver lesions were collected,all of them were proved by clinic and imaging.It included liver vascular malformation（n=1）,hepatocellular carcinoma（n=4）,cholangiocellular carcinoma（n=3）,metastatic tumor in liver（n=2）,liver haemangioma（n=5）,and liver cyst（n=3）.MR imaging were performed with conventional T1WI,T2WI,SWI and dynamic Gd-DTPA contrast enhanced MRI.The SWI imagings were compared to conventional sequence imagings.3D MRA were performed in liver vascular malformation（n=1） and post-gadolinium enhanced SWI performed in one liver haemangioma.Results： In liver vascular malformation（n=1）,SWI was better than conventional MRI and 3D MRA in discovering abnormal veins.SWI could discover tumor vascular structure and degradation products of blood in hepatocellular carcinoma（n=4）,cholangiocellular carcinoma（n=3） and metastatic tumor in liver（n=2）.SWI showed homogeneous slight hyper-signal in liver haemangioma（n=5） and liver cyst（n=3）,and in comparatively large lesion of which the adjacent vein was compressed.Conclusion： SWI surpassed conventional MRI sequences in discovering liver venous vascular malformation and vascular structure in tumor.SWI is very helpful in differential diagnosis of focal liver lesions.It is a new approach to investigate the internal structures of focal liver lesions.

关 键 词：肝疾病 磁共振成像 

分 类 号：R575[医药卫生—消化系统] R445.2[医药卫生—内科学]