子宫颈上皮病变18304例临床病理分析  

Cervical epithelial lesions:a clinicopathologic analysis of 18304 cases

作　　者：王东存[1] 叶明[1] 王莉[1] 

机构地区：[1]新疆医科大学附属肿瘤医院病理科,乌鲁木齐830011

出　　处：《临床与实验病理学杂志》2010年第6期692-695,共4页Chinese Journal of Clinical and Experimental Pathology

摘　　要：目的通过对新疆医科大学附属肿瘤医院18304例不同时期、不同年龄段、不同民族之间子宫颈癌、子宫颈上皮内瘤变(cervical intraepithelia lneoplasia,CIN)的检出率分析,了解其发病状况的变化。方法对1989～2009年间18304例子宫颈上皮病变组织病理学检查结果及患者的年龄、民族分布进行回顾性分析。结果 (1)子宫颈癌共检出5891例,55～64岁年龄段检出率最高(51.71%),其中维吾尔族检出4440例(75.37%);子宫颈癌检出率呈逐渐下降趋势(57.73%→18.78%)。(2)CIN共检出2601例,CIN1和CIN2～3分别在30～34岁、35～39岁年龄段检出率最高(6.11%,14.25%),平均年龄有年轻化趋势(P<0.01);汉族共检出1745例(67.09%);检出率呈逐渐上升趋势(CIN11.20%→6.72%,CIN2～33.50%→13.26%)。(3)子宫颈癌病理类型以中分化鳞状细胞癌为主(66.13%),其中维吾尔族2957例(75.90%)。结论 (1)子宫颈癌的检出率呈逐年下降趋势,55～64岁年龄段检出率最高,其中维吾尔族最多。(2)CIN的检出率呈逐年上升趋势,30～39岁年龄段检出率最高,平均年龄有年轻化趋势,汉族最多。(3)子宫颈癌病理类型以中分化鳞状细胞癌为主,维吾尔族最多。Purpose To analyse the detection rate of cervical carcinoma and cervical intraepithelial neoplasia（CIN） in different stage,different age and different race during the past 21 years in Affiliated Tumor Hospital of Xinjiang Medical University,and to observe the changes of the cervical carcinoma and CIN incidence.Methods The patient’s age,race and pathological characteristics of the cervical epithelial lesions were retrospectively analyzed in 18 304 cases during 1989～2009.Results In 5 891 cases of cervical carcinoma detected,the highest detection rate in 55～64 years old,in which 4 440（75.37%） cases were Uighur.The detection rate of cervical carcinoma was gradually decreased（57.73%→18.78%） with age.2 601 cases of CIN had been detected,patients with CIN1 and CIN2～3 appeared mainly in 30～34 and 35～39 years old,respectively.The average age of CIN was gradually decreased（P0.01）,and 1 745（67.09%） cases were Han.The detection rate of CIN was gradually increased（CIN1：1.20%→6.72%;CIN2～3：3.50%→13.26%）.Most common histological type of cervical carcinoma in this study was moderately-differentiated squamous cell carcinoma（66.13%）,most of which were Uighur（2957 cases,75.90%）.Conclusions The detection rate of cervical carcinoma is gradually decreased with age,which is most frequently detected in 55～64-year-old Uighur.The detection rate of CIN is gradually increased with age：the highest detection rate in 30～39-year-old Han.Most common histological type is moderately-differentiated squamous cell carcinoma in cervix,mainly in Uighur.

关 键 词：子宫颈肿瘤 子宫颈上皮内瘤变 年龄 民族 

分 类 号：R737.33[医药卫生—肿瘤]