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作 者:李继英[1] 赵杨[1] 张臻年[1] 王敬卿[1] 范刚启[1] 张晖[1] 黄迟[1] 刘孔江[1] 郭志力[1] 陆艳[1] 顾兆军[2] 顾成光[3] 蒋晓林[4] 张红[5] 全亚萍[6] 陆卫卫[7] 朱建军 蔡忠明 孙菊光
机构地区:[1]南京市中医院,210001 [2]江苏省第二中医院 [3]连云港市中医院 [4]徐州市中心医院 [5]无锡市中医院 [6]泰州市中医院 [7]南通市中医院 [8]常州市中医院 [9]扬州市中医院 [10]徐州市中医院
出 处:《临床神经病学杂志》2010年第6期469-471,共3页Journal of Clinical Neurology
基 金:南京市重大医学课题项目(ZKX0309)
摘 要:目的比较通脑活络针刺法与常规疗法治疗急性脑梗死(AC I)的疗效及通脑活络针刺法治疗AC I的最佳治疗时间窗。方法采用多中心、随机、对照的研究方法,将145例AC I患者(针刺治疗组)按病程分为〈6 h、6~48 h、〉48 h亚组,在常规治疗的基础上,给予通脑活络针刺法治疗,每天1次,连续14 d。治疗前后进行美国国立卫生研究院卒中量表(NIHSS)评分和Barthel指数(B I)评定;治疗后90 d评定疗效;并与125例常规治疗的AC I患者(常规治疗组)进行比较。结果治疗后,针刺治疗组各亚组的总有效率(96.4%、90.9%、80.4%)显著高于常规治疗组各亚组(86.7%、75.0%、58.3%)(均P〈0.01);针刺治疗组中,〈6 h亚组的总有效率明显高于6~48 h亚组和〉48 h亚组(P〈0.05~0.01)。针刺治疗组各亚组NIHSS评分明显低于、B I明显高于常规治疗组各亚组(均P〈0.01);针刺治疗组中,〈6 h亚组明显优于6~48 h亚组和〉48 h亚组(P〈0.05~0.01)。结论通脑活络针刺法治疗AC I的疗效显著,并且在发病6 h内开始治疗为最佳。Objective To compare the curative effects between Tongnaohuoluo acupuncture therapy and the conventional therapy on acute cerebral infarction(ACI),and the best therapeutic time window of Tongnaohuoluo acupuncture therapy on ACI.Methods By the methods of multi-centered,randomized and controlled,145 ACI patients(acupuncture therapy group) according course were divided into 6 h sub-group,6-48 h sub-group and 48 h sub-group.Based on conventional treatment,Tongnaohuoluo acupuncture therapy was given once daily for 14 d.The score of National Institute of Health stroke scale(NIHSS),Barthel index(BI) pre and post treatment were evaluated.Ninety d after treatment,the curative effects were assessed and compared with other 125 ACI patients who only taken conventional therapy(conventional therapy group).Results After treatment,the total effective rates in each acupuncture therapy sub-group(96.4%,90.9%,80.4%)were significant higher than those in each conventional therapy sub-group(86.7%,75.0%,58.3%)(all P0.01);and in acupuncture therapy group,which in6 h sub-group was significantly higher than 6-48 h and 48 h sub-groups(P0.05-0.01).Compared with each conventional sub-group,NIHSS scores in the each acupuncture sub-group was significantly lower and BI was significantly higher(P0.05-0.01);and in acupuncture therapy group,which in 6 h sub-group were superior to 6-48 h and 48 h sub-groups(P0.05-0.01).Conclusions Tongnaohuoluo acupuncture therapy for ACI has remarkable efficacious.The best time of this therapy is within 6 h after ACI onset.
分 类 号:R743.3[医药卫生—神经病学与精神病学]
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