盐酸法舒地尔治疗缺血性脑卒中疗效观察  

Efficacy observation of Fasudil Hydrochloride in treatment of ischemic stroke

作　　者：孔丽琴[1] 

机构地区：[1]大连医科大学附属第一医院药剂科,辽宁大连116011

出　　处：《中国医药导报》2011年第5期52-53,共2页China Medical Herald

摘　　要：目的:探讨盐酸法舒地尔在改善缺血性脑卒中患者的神经功能缺损评分中的作用。方法:130例确诊的急性脑卒中患者随机分为治疗组和对照组,在常规治疗的基础上,治疗组给予法舒地尔治疗,对照组给予苦碟子治疗,比较2周后两组患者的神经功能缺损评分情况,并进行临床疗效评价。结果:治疗后两组患者的神经功能缺损评分均较治疗前明显改善,差异有高度统计学意义(P<0.01),且治疗组患者神经功能缺损评分改善情况较对照组更显著,差异有统计学意义(P<0.05)。结论:盐酸法舒地尔可显著改善脑卒中患者的神经功能缺损评分,改善患者的神经功能恢复和预后,具有较好的安全性。Objective： To explore the function of Fasudil Hydrochloride on neurological functional deficit score（NFDS）in ischemic stroke patients.Methods： One hundred and thirty cases with ischemic stroke were randomly and averagely divided into two groups,the treatment group and the control group,on the basis of regular treatments,the treatment group were treated with Fasudil and the control group were treated with Ku diezi,the neurological functional deficit score were compared and the clinical effccts were evaluated in two groups after two weeks.Results： The NFDS in two groups were obviously improved,there was significant differences before and after treatment（P0.01）,and its more significant in the treatment group than that in control group（P0.05）.Conclusion： Fasudil Hydrochloride could improve the NFDS in ischemic stroke patients,improve the recovery of nerve function and prognosis,had a better security.

关 键 词：法舒地尔 缺血性脑卒中 神经功能缺损评分 

分 类 号：R743.3[医药卫生—神经病学与精神病学]