^(18)F-FDG PET/CT显像在诊断乳腺癌中的价值  

Value of ^(18)F-FDG PET/CT in diagnosing breast cancer

作　　者：郭佳[1] 陈跃[1] 

机构地区：[1]泸州医学院附属医院核医学科,四川泸州646000

出　　处：《四川医学》2011年第2期258-260,共3页Sichuan Medical Journal

摘　　要：目的探讨18F-脱氧葡萄糖(Fluorine-18 fluorodeoxyglucose,FDG)正电子发射计算机断层显像(positrone mission computer tomography,PET/CT)在乳腺癌术前诊断中的价值。方法 27例乳腺包块的女性患者,PET/CT全身显像行鉴别诊断和分期。PET/CT结果由手术病理证实。结果病理证实15例为乳腺癌,12例为良性包块。15例中PET/CT诊断阳性14例,漏诊1例,其它影像学方法(CT、乳腺钼靶、超声)诊断11例;12例中PET/CT诊断阴性10例,误诊2例,其它影像学方法诊断阴性7例。PET/CT在诊断乳腺癌的灵敏度、特异性、准确性、阳性预测值和阴性预测值分别为14/15(93.3%)、10/12(83.3%)、24/27(88.8%)、14/16(87.5%)、10/11(90.1%)。病理证实15例乳腺癌中的12例有同侧腋窝淋巴结转移,18F-FDGPET/CT诊断阳性10例,假阴性2例。结论 18F-FDGPET/CT显像是鉴别诊断乳腺癌的较准确方法。Objective To evaluate the value of 18F-FDG PET/CT in diagnosing in breast cancer.Methods 27 female with breast masses were performed 18F-FDG PET/CT for identification and diagnosis.The results of PET/CT were proved by pathologic results of surgery.Results 15 masses were malignant and the other 12 were benign.18F-FDG PET/CT diagnosed 14 true positive and missed 1（other imaging modalities diagnosed 11 true positive）.18F-FDG PET/CT diagnosed 10 true negative and 2 false positive （other imaging ways diagnosed 7 true negative）.The sensitivity,specificity,accuracy,positive predictive value and negative predictive value obtained by 18F-FDG PET/CT in diagnosing breast cancer were 14/15（93.3%）、10/12（83.3%）、24/27（88.8%） 、14/16（87.5%）、10/11（90.1%）、respectively.12 cases with malignant lesions were proved axilla lymph metastasis,and 18F-FDG PET/CT diagnosed 10 true positive and 2 false negative.Conclusion 18F-FDG PET/CT imaging can reliably identify and diagnose malignant lesions from breast masses.

关 键 词：正电子发射计算机断层显像 18F-氟代脱氧葡萄糖 乳腺癌 

分 类 号：R737.9[医药卫生—肿瘤] R814.42[医药卫生—临床医学]