卵巢肿瘤的血液动力学研究  

STUDY OF BLOOD FLOW DYNAMICS OF OVARIAN TUMOR

作　　者：刘培淑[1] 傅庆诏[1] 刘韶平[1] 张翠萍[1] 

机构地区：[1]山东医科大学附属医院

出　　处：《山东医科大学学报》1999年第3期231-232,238,共2页Acta Academiae Medicinae Shandong

基　　金：山东省科委科研基金

摘　　要：术前 １ 周对 ７５ 例卵巢肿瘤患者（５３ 例良性肿瘤，２２ 例恶性肿瘤）行 Ｃ 超检查及肿瘤内血流检测，并与术后的组织病理学诊断对照。结果：５３ 例卵巢良性肿瘤中 ２１ 例（３９６２％ ），２２ 例卵巢恶性肿瘤中２１ 例（９５４５％ ） Ｃ 超显示结构异常；良性肿瘤的血流高峰收缩速度（ Ｐ Ｓ Ｖ）的平均值为 １４２±８．１ｃｍ ／ｓ，阻抗指数（ Ｒ Ｉ）平均值为 ０．４７８±０．１１９。恶性肿瘤 Ｐ Ｓ Ｖ 的平均值为 ２４２±１１．５ｃｍ ／ｓ， Ｒ Ｉ平均值为 ０４７８±０．１１９。当以 Ｐ Ｓ Ｖ １６ｃｍ ／ｓ 作为区分卵巢良、恶性肿瘤界值时， Ｐ Ｓ Ｖ 诊断卵巢恶性肿瘤的敏感性率和特异性率分别为 ９０９１％ 和 ９０５７％ ；当用 Ｒ Ｉ０７２ 作为区分卵巢良、恶性肿瘤的界值时， Ｒ Ｉ诊断卵巢恶性肿瘤的敏感性率和特异性率分别为 ８６３６％ 和 ６９８１％ ； Ｃ 超诊断恶性肿瘤的敏感性率和特异性率分别为 ９５４５％ 和７１７０％ 。三者的敏感性率差异无显著性，而 Ｐ Ｓ Ｖ 诊断卵巢恶性肿瘤的特异性率明显高于 Ｒ Ｉ和 Ｃ 超检查者，具有显著差异性（ Ｐ＜ ０．０５）。提示用多普勒血流显像技术检测卵巢肿瘤内异常血流的 Ｐ Ｓ ＶSeventy five cases of ovarian neoplasm (53 benign cases, 22 malignant cases) were detected for intraumor blood flow velocity with C mode ultrasound and Doppler flow imaging technique and contrasted to histopathological diagnosis. 21 cases of benign neoplasm (21/53,39.62%) and 21 maligant neoplasm (21/22, 95.45%) had adnormal morphologic fetures suggesting malignang abnormal morphologic fetures. In benign neoplasm the average value of peak systolic velocity (PSV) was detected 14.2±8.1cm/s and the resistance index (RI) was 0.478±0.119. In malignant neoplasm ,the average value of PSV was 24.2±11.5cm/s and the RI was 0.478±0.119. When considering as the cutoff value of PSV 16cm/s and demarcative value RI 0.72 for differentiation of benign or malignant tumors, the sensitive and specifitive rates of PSV in detecting malignant neoplasm were 90.91% and 90.57%, respectively, and the sensitivie and specifitive rates of the RI in malignant tumors were 86.36% and 69.81%, respectively, and those using C mode ultrasound were 95.45% and 71.70%, respectively, There were no singnificant difference in sensitivity among PSV, RI and C ultrasound. Howerver, the specificity of the PSV was significity higher than that of RI and C ultrasound(P<0.05). The PSV obtainted from intratumor abnormal morphologic features with Doppler ultrasonograpy may be used to different malignant from benign ovarian tumors.

关 键 词：卵巢肿瘤 高峰收缩速度 血液动力学 

分 类 号：R737.31[医药卫生—肿瘤]