甲状旁腺癌诊断治疗的研究进展  

Diagnosis and treatment of parathyroid carcinoma

作　　者：张建波[1] 仲伟霞[1] 李胜[1] 

机构地区：[1]山东省肿瘤防治研究院,济南250117

出　　处：《国际外科学杂志》2011年第2期96-99,共4页International Journal of Surgery

摘　　要：甲状旁腺癌是一种罕见的恶性肿瘤，主要临床表现为甲状旁腺功能亢进和继发于高钙血症引起的各种代谢紊乱以及相应组织器官的损害。完善的实验室检查、准确的影像学定位和可靠的组织病理学特征是甲状旁腺癌诊断的重要依据。甲状旁腺癌对放疗、化疗不敏感，肿瘤及其周围受侵组织的“整块切除”是首选的治疗方式。抗PTH免疫治疗作为一种新的治疗方法倍受关注，预后主要取决于初次手术时肿物的完全切除及术后高钙血症的控制及监测。本文综述了甲状旁腺癌诊断和治疗的最新研究进展。Parathyroid carcinoma is a rare maligant tumor. The main clinical symptoms are primary hy- perparathyroidism and all kinds of metabolism disorder and the damage of homologous tissues and organs. The consummate laboratory examination and the accurate imaging localization and the credible histopathologic feature are key points to diagnosis of parathyroid carcinoma. Parathyroid carcinoma is unsensitive to chemo- therapy and radiotherapy, and en bloc resection of the carcinoma is the preferred treatment approach. Anti- PTH immunization as a new treatment of parathyroid carcinoma has been paid close attention. The prognosis of parathyroid carcinoma is mainly depended on whether the tumor was cut off completely and the control as well as the monitor of the symptomatic hypercalcemian after operation. This article reviews the latest researches and introduces the latest advancement in the diagnosis and treatment of parathyroid carcinoma.

关 键 词：甲状旁腺癌 甲状旁腺机能亢进 诊断 

分 类 号：R736.2[医药卫生—肿瘤]