不可切除结直肠癌肝转移的射频消融治疗  

Radiofrequency ablation for patients with unresectable colorectal liver metastases

作　　者：张文俊[1] 胡芳娟[1] 梁文波[1] 

机构地区：[1]大连大学附属新华医院肿瘤科,辽宁大连116021

出　　处：《中华肿瘤防治杂志》2010年第24期2075-2078,共4页Chinese Journal of Cancer Prevention and Treatment

摘　　要：目的:总结射频消融(RFA)在不可切除结直肠癌肝转移(CLM)中的应用,并对治疗现状和发展前景进行分析。方法:检索PubMed及CHKD期刊全文数据库,以"结直肠癌、肝转移、射频消融、分析"为关键词,检索2001-01-2010-03有关"RFA对不可切除CLM中的应用及其价值"方面的文献,纳入分析26篇。结果:RFA单独或联合应用可提高不可切除CLM的疗效,尤其对于直径≤3 cm转移灶的疗效已经得到肯定。结论:RFA提高了不可切除CLM的总体疗效,但仍需要随机大样本循证医学证据,其疗效依赖于RFA技术水平的提高及医生经验的不断积累。OBJECTIVE：To summarize the treatment of RFA for unresectable colorectal liver metastasis（CLM）,and to analyze the treatment status and prospects.METHODS：With ＂colorectal cancer,hepatic metastasis,radiofrequency ablation,analysis＂ as key words ,the literature concerning the values and treatment of RFA for unresectable CLM from January 2001 to March 2010 were searched in the MEDLINE database and CHKD.Totally 26 were included.RESULTS：RFA can increase the efficacy of unresectable CLM separately or in combination with other therapies,especially for ≤3 cm metastases.CONCLUSIONS：RFA improves the overall efficacy of unresectable CLM,but large random samples of Cochrane evidence are needed.The efficacy of RFA depends on the improvement of technologies and the accumulation of medical experience.

关 键 词：结直肠肿瘤 肝转移 射频消融 综述文献 

分 类 号：R735.3[医药卫生—肿瘤]