血清及支气管肺泡灌洗液中CEA测定对肺外周结节性质的临床价值  

Clinical significance in differentiate of peripheral solitary pulmonary nodule by measurement CEA in BALF and serum

作　　者：姜文青 王学坤 

机构地区：[1]山东省青岛海慈医院呼吸内科,山东青岛266033

出　　处：《吉林医学》2011年第5期850-851,共2页Jilin Medical Journal

摘　　要：目的:探讨支气管肺泡灌洗液(BALF)和血清中CEA含量在肺外周结节性质的临床价值。方法:选择42例确诊的外周结节样改变肺癌患者为检测组,40例肺部良性病变患者为对照组,采用化学发光法检测BALF和血清中癌胚抗原(CEA)的变化。结果:肺癌组BALF和血清中CEA的含量均显著高于肺部良性病变对照组(P<0.05),BALF中含量明显高于同期血清中含量。结论:BALF和血清中的CEA测定在肺癌的诊断和肺外周结节性质的鉴别诊断有较高的临床价值。Objective To investigate the value of CEA in differentiate diagnosis of peripheral solitary pulmonary nodule by measuring CEA in bronchoalveal lavage fluid（BALF） and serum.Methods The level of CEA in BALF and serum in 42 patients with lung cancer and 40 patients with benign lung disease by using chemluminescence.Results The level of CEA measuredin BALF and serum was much higher in lung cancer group than that in benign lung disease group（P0.01）and the level of CEA in BALF was higher than that in serum.Conclusion The measurement of CEA in BALF and serum has more value in clinical diagnose and differentiate of periphral solitary pulmonary nodule disease.

关 键 词：肺癌 支气管肺泡灌洗液 

分 类 号：R734.2[医药卫生—肿瘤]