短暂性脑缺血发作患者血清溶血磷脂酸与ABCD2评分的相关性研究  

Relationship between 1ysophosphatidic acid and ABCD2 score in TIA patients

作　　者：郑福浩[1] 于潇华[1] 迟相林[1] 李振光[1] 王道珍[1] 

机构地区：[1]潍坊医学院附属文登中心医院神经内科,山东威海264400

出　　处：《中华临床医师杂志（电子版）》2011年第3期89-92,共4页Chinese Journal of Clinicians(Electronic Edition)

基　　金：国家"973"基金资助项目(G2000056905)

摘　　要：目的检测短暂性脑缺血发作(TIA)患者血清溶血磷脂酸(LPA)水平,研究LPA水平和ABCD2评分的相关性。方法回顾性分析了2007年5月至2010年5月在潍坊医学院附属文登中心医院住院的TIA患者106例,根据ABCD2评分进行分级,比较各个级别LPA水平,同时对两者进行相关性分析。结果血LPA平均水平随ABCD2评分增高而呈现上升趋势,中危组和低危组均低于高危组,低危组低于中危组,差异有统计学意义(P<0.05,0.01)。LPA水平与ABCD2评分存在线性相关。结论 TIA患者ABCD2评分越高,LPA水平也越高,两者呈正相关。Objective To research the relationship between 1ysophosphatidic acid（LPA）concentration and ABCD2 score by detecting LPA concentration in serum of patients of transient ischemia attack（TIA）.Methods Analysing 106 TIA patients from May 2007 to May 2010 in our hospital and compare average LPA concentration between different risk levels by ABCD2 score.Meanwhile,the correlation analysis between them was made.Results As the ABCD2 score increases,there was the trend that the level of LPA becomes greater.The level of LPA is greater in high risk group than in low risk group and mid risk group,and greater in mid risk group than in low risk group（respectively P0.05 or 0.01）,There was linear correlation between LPA and ABCD2 score.Conclusions As the ABCD2 score increases,the level of LPA become greater.There was positive correlation between LPA and ABCD2 score.

关 键 词：脑缺血发作 短暂性 溶血磷脂素类 ABCD2评分 

分 类 号：R743.3[医药卫生—神经病学与精神病学]