外科手术方式对分化型甲状腺癌^(131)I首次清甲的影响  

Effect of operation type on results of first radioiodine ablation in patients with differentiated thyroid cancer

作　　者：程刚[1] 罗加[1] 吕志祥[1] 

机构地区：[1]重庆医科大学附属第一医院核医学科,400016

出　　处：《重庆医学》2011年第8期776-777,共2页Chongqing medicine

摘　　要：目的观察外科手术方式对分化型甲状腺癌(DTC)131I首次残余甲状腺组织的清除或去除治疗(清甲)结果的影响。方法将38例DTC患者依据清甲效果分为成功组和失败组,手术方式主要以甲状腺床区摄131I率和B超测量残余甲状腺体积进行评价。结果手术方式在两组间有明显的差异(P<0.05)。成功组24 h甲状腺床区摄131I率、残余甲状腺体积明显小于失败组[(8.38±6.85)%vs(17.06±6.23)%,P<0.05;(1.95±1.70)cm3vs(5.71±3.53)cm3,P<0.05],24 h甲状腺床区摄131I率与残余甲状腺体积呈正相关(r=0.691,P=0.001)。结论甲状腺床区摄131I率和B超测量残余甲状腺体积可作为评价DTC外科手术方式的良好指标,手术切除越彻底,术后残余甲状腺组织越少,首次清甲效果越好。Objective To evaluate the effect of operation type on the results of first radioiodine ablation in the patients with differentiated thyroid cancer.Methods38 patients with differentiated thyroid cancer were divided into two groups as successful thyroid remnants ablation group and failed group by the results of radioiodine ablation.Operation type was evaluated by thyroid uptake and thyroid remnants volumes measured by B-ultrasound.ResultsThere was significant difference of operation type between successful and failed group.Thyroid uptake and thyroid remnants volumes in successful group were lower than those in failed group[（8.38±6.85）% vs（17.06±6.23）%,P0.05;（1.95±1.70）cm^3 vs（5.71±3.53）cm^3,P〈0.05].24 h thyroid uptake had correlation with thyroid remnants volumes（r=0.691,P=0.001）.ConclusionThyroid uptake and thyroid remnants volumes measured by B-ultrasound can be good markers as evaluation of operation type in the patients with differentiated thyroid cancer.Total or subtotal thyroidectomy and less thyroid remnants volumes help to get successful thyroid remnants ablation.

关 键 词：甲状腺肿瘤 甲状腺全切或次全切术 131I首次清甲 

分 类 号：R736.1[医药卫生—肿瘤]