依达拉奉联合奥扎格雷钠治疗急性脑梗死120例临床观察  

Clinical observation on acute cerebral infarction 120 cases treated with Edaravone and Ozagrel sodium

作　　者：周业旺[1] 

机构地区：[1]广西省钦州市灵山县人民医院神经内科,广西钦州535400

出　　处：《实用临床医药杂志》2011年第3期68-70,共3页Journal of Clinical Medicine in Practice

摘　　要：目的观察依达拉奉联合奥扎格雷钠治疗急性脑梗死的临床疗效及其安全性。方法将240例急性脑梗死患者随机分为治疗组和对照组,各120例。治疗组应用依达拉奉联合奥扎格雷钠治疗,对照组单用奥扎格雷钠,于治疗前及治疗后14 d对患者进行神经功能缺损评分并进行疗效比较。结果治疗后14 d治疗组神经功能缺损与对照组比较差异有统计学意义(P<0.05);治疗14 d,治疗组总有效率为93.3%,对照组总有效率为66.7%,2组比较差异有统计学意义(P<0.05)。2组均无不良反应发生。结论 依达拉奉联合奥扎格雷钠治疗急性脑梗死安全有效。Objective To observe the clinical effect and safety on acute cerebral infarction treated with Edaravone and Ozagrel sodium.MethodsTwo hundred forty patients were divided into the treatment group（120 cases） and control group（120 cases）.The treatment group was treated with Edaravone and Ozagrel sodium.The control group uses the Ozagrel sodium only.In the treatment 14d before and after the treatment to carry on nerve function damage grading to the patient,treats 14 d to carry on the curative effect comparison.Results Treatment of the latter 14 d treatment group nerve function damage and the control group comparison difference has statistical significance（P〈0.05）.14 d treatment group was better than control effect,the total effective rate was 93.3% in treatment group and control group total effectiveness is 66.7 %,two groups had statistically significant difference（P〈0.05）.Both groups had no adverse reactions.Conclusion This combination used to treat acute brain infarction is effective and safe.

关 键 词：依达拉奉 奥扎格雷钠 急性脑梗死 

分 类 号：R743[医药卫生—神经病学与精神病学]