苕溪流域典型断面底泥14种抗生素污染特征  

Investigation of 14 Selected Antibiotics in Sediments of the Typical Cross Sections of Tiaoxi River

作　　者：陈永山[1,2] 章海波[1] 骆永明[1,2] 胡冠九[3] 赵永刚[3] 宋静[1,2] 

机构地区：[1]中国科学院土壤环境与污染修复重点实验室南京土壤研究所,土壤与环境生物修复中心,南京210008 [2]中国科学院研究生院,北京100049 [3]江苏省环境监测中心,南京210036

出　　处：《环境科学》2011年第3期667-672,共6页Environmental Science

基　　金：国家水体污染控制与治理科技重大专项(2008ZX07101-006-05,2008ZX07101-006-06);中国科学院优秀博士学位论文、院长奖获得者科研启动专项资金项目

摘　　要：利用超声波提取-SPE-UPLC/MS/MS,分析了苕溪流域典型断面底泥的14种抗生素污染特征.结果表明,该流域存在一定程度的抗生素污染,单个化合物的检出率均大于70%(n=7).4种四环素类抗生素(四环素、土霉素、金霉素和强力霉素)是该流域主要的抗生素污染种类,并以土霉素和金霉素较为突出,其含量分别在0.1～55.7、0.7～276.6、6.5～131.6和6.0～15.6μg.kg-1之间.苕溪流域周边某一大型规模化养猪场的排水口(入苕溪)底泥的4种抗生素(四环素、土霉素、金霉素和强力霉素)分别达1 794.2、9 287.5、1 823.6和1 149.5μg.kg-1,表明畜禽养殖的兽药四环素类排放可能是苕溪流域底泥抗生素积累的原因之一.另外该处高达251.6μg.kg-1的磺胺嘧啶检出量也不容忽视.The occurrence and distribution of 14 selected antibiotics in sediments of the typical cross sections of Tiaoxi River were analyzed by UPLC /MS /MS.The 14 antibiotics includes tetracycline（TC）,oxytetracycline（OTC）,chlortetracycline（CTC）,doxycycline（DXC）,sulfadiazine（SD）,sulfamethoxazole（SMZ）,sulfamethazine（SMX）,norfloxacin（NFC）,ofloxacin（OFC）,enythromycin-H2 O（ETM-H2 O）,roxithromycin（RTM）,chloramphenicol（CPC）,thiamphenical（TPC） and florfenicol（FFC）.The results show that almost all sediment samples are unavoidably contaminated with antibiotics（detection frequency is more than 70%）,and the dominant contaminants are TC,OTC,CTC and DXC,which range from 0.1 to 55.7,0.7 to 276.6,6.5 to 131.6 and 6.0 to 15.6 μg.kg-1,respectively.The concentration of TC,OTC,CTC and DXC observed are as high as 1 794.2,9 287.5,1 823.6,1 149.5 μg.kg-1 dry weight,in the sediments of the main stream around an outfall of a pig farm respectively.This implied that waste water discharge from animal husbandry was probably one of the main sources to the contamination of these antibiotics in the sediment of Tiaoxi River.Besides the four dominant antibiotics,sulfadiazine should also be concerned due to its high concentration of 251.6 μg.kg-1 in the sediment around the outfall of the pig farm.

关 键 词：抗生素 污染 沉积物 河流 水体 

分 类 号：X131.2[环境科学与工程—环境科学]