磁敏感加权成像在高血压脑微出血中应用价值的探讨  

The application value of magnetic susceptibility weighted imaging in patients with hypertensive cerebral microbleedsing

作　　者：张国华[1] 郑素君[2] 郑辉[1] 高欣[3] 

机构地区：[1]浙江省台州市第一人民医院放射科,浙江台州318020 [2]浙江省台州市第一人民医院泌尿科,浙江台州318020 [3]上海长征医院影像科,上海200003

出　　处：《医学影像学杂志》2011年第1期1-4,共4页Journal of Medical Imaging

基　　金：台州市科技局项目(090KY45)

摘　　要：目的:探讨磁敏感加权成像在高血压脑微出血中的应用价值。方法:采用1.5T MR扫描仪,对48例高血压脑微出血患者分别进行常规和SWI序列扫描,比较各序列对于脑微出血灶的数量、部位、分布的显示情况。结果:T2WI序列检出低信号灶169个,T2FLAIR序列检出低信号灶273个,SWI序列检出低信号灶1335个,各序列显示病灶数量之间的差异具有统计学意义(2=9.92,P<0.05)。微出血病灶分布于基底节区为31.6%,皮层-皮层下为24.9%、脑干为18.7%,丘脑为18.6%,小脑为6.2%。结论:磁敏感加权技术对于高血压脑微出血的显示具有高度敏感性,为目前检出脑微出血的最佳序列。Objective：To explore the application value of susceptibility weighted imaging in patients with hypertensive cerebral microbleeds.Methods：48 patients with hypertension cerebral microbleeds were performed with both SWI and conventional MRI sequences at 1.5 T MR scanner.The quantity,location and distribution of the cerebral microbleeds in all MRI sequences were compared.Results：The number of cerebral microbleeds were 169 detected by T2-weighted image,273 detected by T2 FLAIR and 1335 detected by susceptibility weighted imaging,respectively.There was significant difference between sequences for the detection of cerebral microbleeds（X2=9.92,P0.05）.The locations of microbleeds were basal ganglia（31.6%）,cortex-subcortex（24.9%）,brain stem（18.7%）,thalamus（18.6%）,cerebellum（6.2%）.Conclusion：Susceptibility weighted imaging is of great sensitivity for the detection of hypertensive cerebral microbleeds.This technique is so far the best sequence in detecting the cerebral microbleeds.

关 键 词：高血压 脑微出血 磁敏感加权成像 磁共振成像 

分 类 号：R743.34[医药卫生—神经病学与精神病学] R445.2[医药卫生—临床医学]