具心理障碍的功能性消化不良41例临床分析  

Analysis of 41 cases with functional dyspepsia complicated by psychological disorders

作　　者：贾绮宾[1] 李笠[1] 阴英[1] 樊宇靖[1] 蓝宇[1] 

机构地区：[1]北京积水潭医院消化内科,100035

出　　处：《中华全科医师杂志》2011年第3期207-209,共3页Chinese Journal of General Practitioners

摘　　要：2008年6月至2009年1月我院1320例消化科就诊患者中，功能性消化不良（FD）患者277例（20．9％）；其中经明尼苏达多相人格问卷（MMPI）结论列入心理障碍者为41例，占FD患者的14．8％。41例出现疑病及躯体化倾向者38例92．7％，焦虑与抑郁并存的25例（60．9％）。主诉症状上腹痛40例（97．6％），餐后饱胀31例（75．6％），早饱266例（63．4％），恶心15例（36．6％），烦躁、多虑、乏力、精力不集中、记忆力减退、失眠多梦等主诉占80．0％以上。心理疏导合并抗焦虑抑郁药物治疗4周末，显效5例，有效31例，无效3例，总有效率87．8％。提示，功能性消化不良患者焦虑抑郁情绪发生率较正常人群显著升高。心理障碍患者具有明显的疑病和躯体化倾向。心理疏导配合抗焦虑抑郁药物治疗能取得很好的效果。In our gastroenterology clinic from Jun. 2008 to Jan. 2009, 20. 9% （277/1320） patients were diagnosed with functional dyspepsia （FD） and 14. 8% （41/277） of them with psychological problems according to Minnesota Multiphasic Personality Inventory （MMPI）. In those with psychological disorders, 92. 7% were found with somatization, 60. 9% with depression and anxiety, 97.6% with abdominal pain, 75.6% with bloating, 63.4% with early fullness and 36. 6% with nausea. More than 80% patients with anxiety and depression complained irritability, worry, fatigue, poor concentration, memory loss and insomnia. After 4 weeks of psychological consultation and anti-depression treatment, 5 patients had significant improvement, 31 had improvement and 3 had no response. The overall response rate was 87.8%. In summary,there is a high prevalence of depression and anxiety in population with FD. Hypochondria and somatization are common among these patients. Psychological consultation with anxiolytic drugs may have good therapeutic effects.

关 键 词：消化不良 焦虑 抑郁 

分 类 号：R57[医药卫生—消化系统]