上感颗粒对急性上呼吸道感染患者的退热疗效分析  

Antipyretic Effect of Shanggan Granule in Treatment of Acute Upper Respiratory Tract Infection

作　　者：余衍亮[1] 奚肇庆[1] 张晓云[2] 罗翌[3] 刘清泉[4] 张念志[5] 孙伯青[6] 孙菊光 杜梁枫[8] 郑艳[9] 张丽[9] 耿连艺[9] 张旸[9] 

机构地区：[1]江苏省中医院,南京市汉中路155号210029 [2]成都中医药大学医院 [3]广东省中医院 [4]北京中医药大学附属东直门医院 [5]安徽中医学院第一附属医院 [6]江苏省昆山市中医院 [7]江苏省徐州市中医院 [8]江苏省无锡市第三人民医院 [9]南京中医药大学

出　　处：《中医杂志》2011年第6期486-488,共3页Journal of Traditional Chinese Medicine

基　　金：国家中医药管理局中医药行业科研专项(200807041)

摘　　要：目的观察上感颗粒对急性上呼吸道感染患者的退热效果。方法收集8家医院433例急性上呼吸道感染患者,按照诊断标准分为风寒证、风热证、卫气同病证、风邪袭表(寒热不显)、风邪袭表(寒热兼夹)5个证型。均予上感颗粒口服治疗,每天服用2次,疗程3天。观察1个疗程,测量患者给药后1h、2h、3h、4h、24h内、48h内、72h内、72h的体温,观察即刻退热疗效和解热时间。结果服药4h内退热216例,占49.88%;服药后72h治愈413例,治愈率为95.38%;各证型组间比较差异无统计学意义(P>0.05)。结论上感颗粒治疗急性上呼吸道感染发热疗效确切。Objective To observe the antipyretic effect of Shanggan Granule（Granule for treating upper respiratory tract infection）in treatment of acute upper respiratory tract infection.Methods In this multi-centered controlled trial,433 cases of acute upper respiratory tract infection collected from 8 hospitals were diagnosed as wind heat syndrome,wind cold syndrome,syndrome of both wei and qi being diseased,syndrome of wind attacking the exterior（without significant manifestation of cold or heat）,and syndrome of wind attacking the exterior（with complicated manifestation of cold and heat）.All of them were treated with Shanggan Granule for 3 days,2 times a day.After a 3-day＇s observation,the body temperature of the patients in 1h,2h,3h,4h,24h,48h,and 72h was measured to record the instant antipyretic effect and the cured time.Results The fever was reduced in 216 cases（49.88%）within 4h and cured in 413 cases（95.38%）within 72h after medication respectively.There is no statistically significant difference among all syndromes（P0.05）.Conclusion Shanggan Granule can treat the acute upper respiratory tract infection effectively.

关 键 词：上感颗粒 急性上呼吸道感染 发热 退热疗效 

分 类 号：R259[医药卫生—中西医结合]