磷脂酰丝氨酸的提取分离研究进展  

Research advance in extraction and separation of phosphatidylserine

作　　者：李阅兵[1] 刘承初[1] 谢晶[1] 李应森[2] 李家乐[2,3] 陈苏 

机构地区：[1]上海海洋大学食品学院,上海201306 [2]上海海洋大学省部共建水产种质资源发掘与利用教育部重点实验室,上海201306 [3]上海市高等学校水产养殖学E-研究院,上海201306 [4]美国焯安神经增长因子生物技术有限公司

出　　处：《中国油脂》2011年第3期56-61,共6页China Oils and Fats

基　　金：973计划前期研究专项项目(2009CB126001);上海高校创新团队建设项目;上海市教育委员会重点学科建设项目资助(J50704)

摘　　要：磷脂酰丝氨酸作为人类大脑的益智物质,已经得到了广泛关注。主要对磷脂酰丝氨酸的提取和纯化方法进行介绍。提取方法包括氯仿-甲醇法、叔丁基甲醚法、乙酸乙酯-乙醇法等。纯化的方法涉及薄层色谱法、柱色谱法、高效液相色谱法等。磷脂酰丝氨酸提取工艺复杂,需使用大量有机溶剂,今后需加强提取工艺的优化。Phosphatidylserine, as the nootropics substances of human brain, has been concerned widely. The extraction and purification methods of phosphatidylserine were introduced. The extraction methods included chloroform -methanol method, tert -butyl methyl ether method and ethyl acetate -ethanol method. Purification methods included thin layer chromatography,column chromatography and HPLC. The extraction technics of phosphatidylserine were complicated, the optimization of them should be enhanced. and abundant organic solvent was consumed, sothe optimization of them should be enhanced.

关 键 词：磷脂酰丝氨酸 溶血磷脂酰胆碱 提取 纯化 色谱 洗脱 

分 类 号：TQ464.7[化学工程—制药化工]