多烯磷脂酰胆碱治疗原发性肝癌TACE后肝损伤的研究  

Study on the treating of hepatic injury of primary liver cancer after TACE with Polyene Phosphatidylcholine

作　　者：陆英[1] 王东盛[1] 王成纲[1] 刘明[1] 刘海洋[1] 

机构地区：[1]北京煤炭总医院介入科,北京100028

出　　处：《中国医药导报》2011年第8期77-78,共2页China Medical Herald

摘　　要：目的:观察多烯磷脂酰胆碱治疗原发性肝癌患者行肝动脉化疗栓塞(transcatheter arterial chemoembolization,TACE)后发生肝损伤的疗效。方法:60例原发性肝癌患者,随机分为两组,每组各30例,均给予TACE治疗。治疗组在常规保肝治疗基础上加用多烯磷脂酰胆碱静点,930 mg/d;对照组给予常规保肝治疗。结果:两组转氨酶、胆红素在TACE后均明显升高(P<0.01),血清前白蛋白均明显降低(P<0.01)。经多烯磷脂酰胆碱治疗后,治疗组各指标均较对照组明显好转(P<0.05)。结论:多烯磷脂酰胆碱治疗原发性肝癌患者TACE后肝损伤效果良好,能改善患者的预后。Objective： To study the therapeutic efficacy of Polyene Phosphatidylcholine for patients with hepatic injury of primary liver cancer after TACE. Methods： 60 patients with primary liver cancer were devided into the treatment group and the control group, they were treated by TACE. The treatment group were treated by Polyene Phosphatidylcholine. The control group were treated by general remedy. Results： Transaminase and bilirubin rised and Prealbumin （PA） reduced in two groups after TACE, but there were significantly difference after treatment in the treatment group compared with the control group （P〈0.05）. Conclusion： The therapeutic efficacy of Polyene Phosphatidylch01ine for patients with hepatic injury of primary liver cancer after TACE is satisfied and could improve prognosis.

关 键 词：多烯磷脂酰胆碱 原发性肝癌 经导管动脉化疗栓塞 肝损伤 预后 

分 类 号：R735.7[医药卫生—肿瘤]