磁共振扩散加权成像在膀胱病变的应用初探  

MR Diffusion--Weighted Imaging in Bladder Lesions：Preliminar Study

作　　者：袁程[1] 路青[1] 许建荣[1] 徐骁[1] 朱震亚[1] 华佳[1] 

机构地区：[1]上海交通大学医学院附属仁济医院放射科,上海200127

出　　处：《实用放射学杂志》2011年第2期238-241,258,共5页Journal of Practical Radiology

摘　　要：目的初步探讨扩散加权成像（DWI）及表观弥散系数（ADC）在膀胱癌诊断评估中的应用价值。方法对45例膀胱癌占位患者行DWI及常规MR序列扫描。比较不同b值下膀胱病灶的ADC值及图像效果；分析DWI与常规序列显示膀胱病灶能力的差异；比较膀胱病灶与周围组织ADC值有无差异。结果b值取700s／mm。时膀胱病灶平均ADC值显著高于1500s／mm。的ADC值。DWI发现膀胱病灶的准确率为98．1％，常规MR序列为96．2％。b值取1500s／mm。时膀胱癌平均ADC值（0．75±0．12）×10^-3mm^2／s，显著低于膀胱炎（1．39±0．13）×10^-3mm^2／s、病灶周围正常膀胱壁（1．42±0．07）×10^-3mm^2／s、尿液（2．69±0．13）×10^-3mm^2／s（P〈0．05）。结论DWI及ADC值对膀胱癌的诊断评估具有较好的应用价值，是对常规MR检查有意义的补充。Objective To preliminary evaluate the application of MR diffusion--weighted imaging（DWI）and apparent diffusion coefficient（ ADC） in diagnosis of bladder carcinoma . Methods DWI and conventional MR imaging were performed in 45 patients with bladder lesions . The ADC value of bladder lesions and the image quality with different b values were analysed . The ability of DWI and conventional MR imaging in detecting the bladder lesions was compared . The ADC values of the bladder lesions and sur- rounding structures were measured and analysed respectively. Results The mean ADC value of bladder lesions was higher at low b value （700 s/ram2） than that at high b value（1500 s/ram2 ）. The accuracy in detection of bladder lesions by DWI was 98. 1% ,and was 96.2 % by conventional MR imaging. The mean ADC value（ ×10^-3mm^2/s） of the urinary bladder carcinoma was（0.75±0.12） , which was significantly lower compared with that of bladder inflammation（ 1.39±0.13）, the surrounding normal bladder wall of the lesion（ 1.42 ±0.07）and urine（2.69±0.13）. Conclusion DWI and ADC values are useful in diagnosis and evaluation of the bladder carcinoma, and are helpful to add in conventional MR sequences.

关 键 词：膀胱 膀胱癌 磁共振成像 

分 类 号：R737.14[医药卫生—肿瘤] R445.2[医药卫生—临床医学]