合成生命之探索——人造噬藻体  

Artificial Cyanophage——A Trail Leading to Artificial Life

作　　者：胡志红[1] 陈新文[1] 娄治平[2] 赵进东[3] 

机构地区：[1]中国科学院武汉病毒研究所,武汉430071 [2]中国科学院生命科学与生物技术局,北京100864 [3]中国科学院水生生物研究所,武汉430072

出　　处：《中国科学院院刊》2011年第2期179-183,共5页Bulletin of Chinese Academy of Sciences

摘　　要：人造生命是多种学科交叉、高新技术集成的系统工程,随着科学技术的发展,特别是基因组全人工合成技术的形成,这个梦想的实现开始变得可能。噬藻体是原核藻类(蓝细菌)的病原,结构相对简单,人工合成噬藻体、阐明其感染并杀灭蓝细菌的分子机制,有望实现对水华蓝藻的噬藻体控制,并可为人工合成更复杂的生命形式奠定理论基础和技术基础。Artificial life has been a dream of mankind and could come to fruition with the aid of collaborative andcohesive interactions of different disciplines including systematic engineering.The development of de novelsynthesis techniques,it is no longer a dream but a practical reality and it is expected to bring evolution to bio-technology.Cyanophage is a kind of phage that infects cyanobacteria,which are causative agents of water bloom.Synthesis of a cyanophage genome has the potential to create a cyanophage that can lyse cyanobacteria andtherefore provide a new strategy to control water bloom.The research of artificial cyanophage is a trail leading tolarge genome synthesis and the results will help to understand many basic questions in life sciences.

关 键 词：人造生命 人工噬藻体 水华 

分 类 号：Q819[生物学—生物工程]