甲状腺乳头状增生病理形态探讨  

作　　者：王红霞[1] 张金成[1] 

机构地区：[1]广东南方医科大学附属小榄医院,中山528415

出　　处：《中国社区医师（医学专业）》2011年第7期159-160,共2页

摘　　要：目的:探讨甲状腺良、恶性乳头状增生的病理形态、鉴别诊断及预后情况。方法:收集术后患者有随访记录的临床病理资料,包括乳头状增生的弥漫性毒性甲状腺肿(Grave's病)、结节性甲状腺肿、甲状腺滤泡性腺瘤及甲状腺乳头状癌,重新观察HE切片。结果:良性乳头分支1～2,乳头间质纤维组织稀少,滤泡胶质丰富,细胞形态呈单层立方、柱状,无毛玻璃核,不伴砂砾体,乳头结构与周围组织分界清;恶性乳头分支2个以上,乳头间质纤维硬化明显,少许滤泡胶质,有毛玻璃细胞核,伴有砂砾体,乳头结构与周围组织界线不清。结论:乳头形态、细胞形态及乳头周围组织改变,是诊断和鉴别诊断良、恶性乳头状增生病变组织学依据。良性乳头预后较好。Objective：To investigate the pathologieal morphology, differential diagnosis, and prognosis of benign and malignant thyroid papillary hypeplasia. Method： Collect clinical and pathological information of patients after - operation, including papillary. hyperplasia with diffuse toxic goiter （ Graveg disease）, nodular goiter, follicular thyroid adenuma and thyroid papillary carcinoma, re -observe the HE sections. Results：In cases with 1 -2 branches of benign papillary, the papillary interstitial fibrosis is rare,with rich follicular eolloid,the cells are simple euboidal, colunmar, without frosted glass nuclei nor sand body, and there is clear boundary between the nipple and surrounding tissue; In cases with more than 2 branches of malignant papillary,there is significant hardening in nipple interstitial fibrosis, with some follicular colloid, ground glass nuclei and sand body, and the boundary between nipple and surrounding tissue is unclear. Conclusions ： Nipple and the cells form of organization and around them, is the most innocent, the diagnosis and malignant papillary growths on the organizational learning.

关 键 词：甲状腺 乳头状增生 病理形态 鉴别诊断 

分 类 号：R736.1[医药卫生—肿瘤]