盐酸帕罗西汀提高癫痫后抑郁患者生活质量的临床研究  

Study on the Paroxetine to Improve the Quality of life in Post-Epilepsy Depression

作　　者：赵晓娟[1] 权青云[1] 杨嫣华[1] 林芝惠[1] 徐晓霞[1] 李宏图[1] 

机构地区：[1]武警陕西总队医院神经内科,陕西西安710054

出　　处：《临床医学工程》2011年第3期399-400,共2页Clinical Medicine & Engineering

摘　　要：目的研究帕罗西汀对癫痫后抑郁患者生活质量提高的疗效。方法对93例癫痫后抑郁的患者随机分成帕罗西汀治疗组(48例)和不使用帕罗西汀的对照组(45例)。两组患者均于治疗前、治疗4周、10周、24周由专人进行Beck抑郁问卷(BDI)测定及QOLIE-31量表测定。结果治疗组在治疗10周及24周,与对照组及治疗前相比较,均有统计学意义(P<0.05)。结论帕罗西汀对癫痫后抑郁有显著的疗效,明显提高癫痫后抑郁患者的生活质量。Objective To explore the effect of the quality of life defect of paroxetine in treatment of post-epilepsy depression. Methods 93 cadres transferred to civilian work were randomly investigated by paroxetine group （48 cases） and control group （45 cases）. We estimated the curative effect with BDI TABLE and QOLIE-31 TABLE on prior treatment and after treated 4, 10, 24 weeks. Result The cadres transferred to civilian work were quite different after treated 10 weeks and 24 weeks （P〈0.05）. Conclusion It suggests that paroxetine can treat post-epilepsy depression and improve symptoms of the quality of life.

关 键 词：帕罗西汀 癫痫 抑郁 生活质量 

分 类 号：R749.17[医药卫生—神经病学与精神病学]