乳房外Paget病一例  

A case of extra-mammary Paget＇s disease

作　　者：齐淑贞[1] 徐秀莲[1] 曾学思[1] 胡云峰[2] 王千秋[1] 沙仲[1] 

机构地区：[1]中国医学科学院北京协和医学院皮肤病医院,南京210042 [2]暨南大学附属第一医院皮肤科

出　　处：《国际皮肤性病学杂志》2011年第2期66-67,共2页International Journal of Dermatology and Venereology

摘　　要：患者男,54岁,阴囊及股部赘生物4个月.皮肤科检查：右侧腹股沟及阴囊见多个红色或皮色的结节和肿块,直径为0.5 cm×0.5 cm～8 cm×8 cm,呈疣状或圆顶状,部分表面糜烂,有少许脓性分泌物,伴恶臭.该患者在以往的皮损基础上出现新生物,伴有恶臭,根据患者的临床表现及病史考虑为鳞状细胞癌,给予进一步检查,经皮损组织病理和免疫组化的检查诊断为原发性乳房外Paget病.实验室检查HPV为阴性.A 54-year-old man presented with neoplasms on the groin and scrotum for 4 months.Physical examination revealed multiple, erythematous or skin-colored, verrucous-like or dome-shaped nodules and neoplasms measuring 0.5 to 8 cm in diameter on the right groin and scrotum. Erosions were observed on the surface of some lesions with purulent secretion and stench. The neoplasms arose in previous lesions with stench. The patient was initially diagnosed with squamous cell carcinoma according to the clinical manifestation and medical history, but histopathological and immunohistochemical examination confirmed a diagnosis of primary extra-mammary Paget＇s disease. PCR was negative for low- or high-risk human papilloma virus types in this patient.

关 键 词：佩吉特病 乳腺外 免疫组织化学 

分 类 号：R739.5[医药卫生—肿瘤]