原发性慢性闭角型青光眼的初始治疗策略  

The initial treatment strategy of primary angle-closure glaucoma

作　　者：梁远波[1] 荣世松[1] 王宁利[1] 唐炘[1] 赵家良[2] 

机构地区：[1]首都医科大学附属北京同仁医院北京同仁眼科中心北京市眼科学与视觉科学重点实验室,100730 [2]中国医学科学院中国协和医科大学北京协和医院眼科研究中心

出　　处：《眼科》2011年第1期1-4,共4页Ophthalmology in China

基　　金：科技部十一五科技支撑计划项目(2007BAI18B08)

摘　　要：中国是世界上原发性闭角型青光眼(PACG)患者最多的国家。目前在中国对于慢性PACG的治疗方案一直主张将小梁切除术作为房角粘连性关闭大于180°范围者的首选治疗措施,此治疗模式可归纳为"手术–药物–二次手术(SMS)"治疗策略。而国际上多个指南则推荐"激光周边虹膜切开术(LPI)–药物–手术(LMS)"的序贯性治疗策略。在慢性PACG的治疗时是采用LMS治疗策略还是中国现行的SMS治疗策略,哪种更适合于中国国情,迄今尚无直接对比研究的临床试验证据。China has the largest population of primary angle-closure glaucoma（PACG）.Trabeculectomy is currently suggested as the initial therapy for chronic PACG with peripheral anterior synechia greater than 180 degree of the angle,which is summarized as surgery-medication-surgery（SMS） strategy.In comparison,multiple international glaucoma guidelines adopt laser peripheral iridotomy（LPI） as the initial treatment of a stepwised sequenced strategy,LPI-medication-surgery（LMS）.Until now,few prospective study on SMS and LMS strategy has been conducted.It is hard to draw a conclusion on which strategy would be more suitable among Chinese chronic PACG patients.Therefore,robust evidence is in great demand considering the characteristics of Chinese patients and the socioeconomical level.

关 键 词：青光眼 闭角型/治疗 激光周边虹膜切开术 小梁切除术 

分 类 号：R775[医药卫生—眼科]