中枢神经细胞瘤94例临床分析  

Central neurocytomas：clinical analysis of 94 cases

作　　者：钱海鹏[1] 林松[2] 曹勇[2] 隋大立[2] 姜中利[2] 张懋植[2] 

机构地区：[1]中国医学科学院肿瘤医院头颈神经外科 [2]首都医科大学附属北京天坛医院神经外科,100050

出　　处：《中华神经外科杂志》2011年第2期162-165,共4页Chinese Journal of Neurosurgery

基　　金：国家973计划专项课题（2007CB512503）

摘　　要：目的 总结中枢神经细胞瘤临床特点,探讨其治疗策略.方法 回顾性分析94例中枢神经细胞瘤患者临床资料.全部行手术治疗,肿瘤全切除66例,近全切除26例,部分切除2例;分析总结中枢神经细胞瘤的临床、病理、影像特点.结果 死亡2例,随访84例,术后放疗56例,肿瘤复发4例.多数患者生存良好.结论 中枢神经细胞瘤多发于室间孔附近侧脑室系统,手术全切除是最佳治疗手段,未全切患者术后放疗可减少复发率.Objective To analyze the clinical characteristics of central neurocytomas,and discuss the therapeutic strategies.Methods 94 cases of central neurocytomas were studied retrospectively.All patients underwent operation with removal of the tumor through either transcallosal or transcortical approach.Total resection was achieved in 66 patients,subtotal resection in 26 patients and partial resection in 2 patients.The clinical,radiological,histologic and immunohistochemical features of these patients were reviewed and analyzed.Methods Amongthe 94 cases of central neurocytomas,two died after surgery.Among the 84 followed- up cases,56 cases underwent postoperative radiotherapy,4 cases had recurrence.Most patients have favorable prognosis.Conclusion Central neurocytomas occur mostly in the lateral ventricle near the Monro＇s foramen.Total resection is the best treatment.Postoperative radiotherapy for partially removed tumors may reduce the possibility of recurrence.

关 键 词：中枢神经细胞瘤 脑室肿瘤 显微外科手术 预后 

分 类 号：R739.4[医药卫生—肿瘤]