超声引导微波凝固治疗大肝癌的临床应用  

Clinical Application of Ultrasornd-Guided Percutaneous Microwave Coagulation Therapy(PMCT) for Large Pepatocellular Carcinoma

作　　者：蒲春华[1] 黄柱华[2] 尹正银[3] 

机构地区：[1]安徽省蚌埠医学院第一附属医院康复部B超室,233004 [2]蚌埠医学院第一附属医院康复部肿瘤内科 [3]蚌埠医学院第一附属医院B超室

出　　处：《中华全科医学》2011年第4期635-636,共2页Chinese Journal of General Practice

摘　　要：目的探讨超声引导经皮穿刺微波凝固(percutaneous microwave coagulation therapy,PMCT)治疗大肝癌的效果。方法对24例患者33个瘤体行超声引导下经皮穿刺微波凝固治疗。根据肿瘤大小,选择不同微波功率和作用时间。结果治疗后显示肿块出现不同程度的缩小,内部回声增强;彩色多普勒显示肿瘤内血流减少或消失。本组病例的1,3,6个月及其后生存率分别为:100.0%(24/24)、83.3%(20/24)、66.6%(16/24)4、1.7%(10/24)。中位生存期10.5月。完全缓解(CR):11.8%(5/24);部分缓解(PR):58.3%(14/24);总有效率为70.1%。未发生严重并发症和不良反应。结论经皮穿刺微波凝固治疗大肝癌是一种有效、安全、简便的方法,可明显提高生存率,值得临床进一步研究。Objective To study the effect of Uhrasornd-guided percutaneous microwave coagulation therapy （PMCT） for large hepatocellular carcinoma. Methods 24 patients with large hepatocellular carcinoma including 33 tumous nodes were treated by PMCT. The different frequency and time were selected according to tumor size. Results After treatment all nodules dwindled in size, the internal echo strengthened color tratumuoral blood flow signals decreased or disappeared. The survival rate of 1,3,6 months and after were 100.0% （24/24） ,83.3% （20/24） ,66.6% （16/24） ,41.7% （10/24） ,respectively. Median survival time was 10.5 months;CR was 11.8% （5/24） and PR was 58.3% （14/24） ;the total effective rate was 70.1%. There were no serious complications or side effect in all patients. Conclusion PMCT was an effective, safe and convenient therapy method in treating hepatocellular carcinoma,which can improve patients＇ survival rate and should be further investigated.

关 键 词：大肝癌 超声引导 经皮穿刺微波凝固治疗 

分 类 号：R735.7[医药卫生—肿瘤]