抗癌方联合TACE治疗气虚血瘀型原发性肝癌的临床观察  

Clinical observation on anti-cancer decoction combined with TACE for HCC in Qi-deficiency and blood stasis

作　　者：周小舟[1] 孙新锋[1] 马文峰[1] 黄俏光[1] 徐文军[1] 占柏林[1] 周大桥[1] 

机构地区：[1]广州中医药大学附属深圳医院国家中医肝病重点专科,广东深圳518033

出　　处：《湖南中医药大学学报》2010年第11期55-57,共3页Journal of Hunan University of Chinese Medicine

基　　金：2007年度深圳市科技局资助项目(200702133)

摘　　要：目的观察抗癌方联合肝动脉化疗栓塞术(TACE)治疗气虚血瘀型原发性肝癌(HCC)对中医证候、甲胎蛋白以及CT复查肿瘤的改善情况,以探讨联合治疗对该病的近期疗效、生存质量及生存率的影响。方法采用前瞻性对照研究,选择64例原发性肝癌(气虚血瘀型)患者,随机分为2组,每组32例,治疗组:TACE治疗基础上口服抗癌方煎剂,对照组:单纯行TACE治疗。结果治疗组与对照组总有效率分别为90.6%(29/32)、65.6%(21/32),肿瘤初次复发率分别为9.37%(3/32)、34.38%(11/32),两组比较差异有统计学意义(P<0.05);联合治疗能有效降低血清甲胎蛋白水平,显著改善中医证候,与对照组比较差异有统计学意义(P<0.05)。结论抗癌方联合TACE治疗气虚血瘀型HCC患者,可以明显改善患者的生存质量、减少肿瘤的复发并提高患者的生存率。Objective To observe the effect of Anticancer decoction combined with TACE for HCC in Qi-deficiency and blood stasis on improving syndrome,AFP and CT result for investigation of ETR,life quality and survival rate.Methods 64 patients with HCC in Qi-deficiency and blood stasis were divided randomly into two groups,32 in each group.The patients in therapeutic groups treated with Anti-cancer decoction combined with TACE and in control group with TACE only.Results The total effective rates in both groups were 90.6%（29/32） and 65.63%（21/32）;the initial tumor recurrence rates were 9.37%（3/32） and 34.38%（11/32）;and the combined treatment to reduce serum level of alpha-fetoprotein in improving TCM syndrome was better than TACE only was（P〈0.05）.Conclusion The combined treatment is effective for HCC in Qi-deficiency and blood stasis,which can improve significantly the survival quality of the patients,reduce reoccurring of the cancer and increase the survival rate of the patients.

关 键 词：原发性肝癌 抗癌方 肝动脉化疗栓塞术 黄芪 白术 莪术 临床研究 

分 类 号：R735.7[医药卫生—肿瘤]