肠内营养制剂在结直肠癌患者术前肠道准备中的临床应用  

Application of enteral nutrition in preoperative bowel preparation for patients with colorectai carcinoma

作　　者：白文启[1] 侯生槐[1] 王立春[1] 粱小波[1] 

机构地区：[1]山西省肿瘤医院结直肠肛门外科,太原 030013

出　　处：《肿瘤研究与临床》2010年第12期830-832,共3页Cancer Research and Clinic

摘　　要：目的探讨结直肠癌患者术前使用肠内营养制剂代替传统流质饮食行肠道准备对患者营养状况和免疫功能的影响。方法将68例结直肠癌患者随机分为研究组和对照组，分别于术前3dV1服整蛋白型肠内营养剂和传统流质饮食，比较两组患者术后第1天的营养状况和免疫指标。结果两组患者肠道清洁度均好，研究组术后第1天的营养指标淋巴细胞总数、血红蛋白、血清总蛋白、血清清蛋白、前清蛋白、转铁蛋白和免疫指标CD^＋3、CD＾4、CD^＋8及CD＾＋4/CD＾＋8比值较肠道准备前变化不明显。对照组术后第1天营养指标淋巴细胞总数、血红蛋白和免疫指标CD^＋3、CD＾4、CD^＋8较肠道准备前变化不明显，而术后第1天血清总蛋白[（65．35±3．02）g／L］、清蛋白[（32．5±1．98）g／L］、前清蛋白［（221．02±22．45）mg／L]、转铁蛋白［（2．12±0．2）g／L]和cD：／cD；（1．14±1．98）均较肠道准备前［分别为（69．43±3．21）g／L、（35．43±2．45）g／L、（236．54±18．45）mg／L、（2．3l±0．03）g／L、1．53±2．45］显著降低。结论术前应用肠内营养制剂代替传统流质饮食行肠道准备能改善患者的营养状况和免疫功能，值得临床推荐应用。Objective To study the safety of enteral nutrition in preoperative bowel preparation for patients with eolorectal carcinoma. Methods 68 patients with colorectal carcinoma were randomized into 2 groups.34 patients in the study group were applied with a kind of enteral nutrition in preoperative bowel preparation.34 patients in the control group were applied with the traditional liquid diet. Results In the study group, the change of the total sum of lymphoeytes, hemoglobin, the serum total protein, albumin, prealbumin, transferrin and immune parameters CD^＋3, CD^＋4, CD^＋8 and CD^＋3/CD^＋8 after operation had no significant difference compared with that before preoperative bowel preparation （P 〉0.05）. But in the control group, the total sum of lymphocytes, hemoglobin and immune parameters CD^＋3, CD^＋4, CD^＋8 after operation had no significant difference compared with that before preoperative bowel preparation, the serum total protein [（65.35±3.02） gill, albumin [（32.5±1.98） g/L], prealbumin [（221.02±22.45） mg/L], transferrin [（2.12±0.2） g/L] and CD^＋3/CD^＋8 （1.14± 1.98） were significantly lower after operation than that before preoperative bowel preparation [（69.43±3.21） g/ L, （35.43±2.45） g/L, （236.54±18.45） rag/L, （2.31±0.03） g/L, 1.53±2.45] （P〈0.05）. Conclusion Enteral nutrition could be applied to the preoperation bowel preparation and replace the traditional liquid diet. As a simple way, it can make the colon clear, improve the nutrition and immunity status of the patients.

关 键 词：结直肠肿瘤 肠内营养 肠道准备 

分 类 号：R735[医药卫生—肿瘤]