进展性卒中相关因素临床分析  

Study of related factors of stroke in progression

作　　者：刘磊[1] 王泽颖[2,3] 李瑞华[1] 

机构地区：[1]潍坊医学院,潍坊261042 [2]潍坊医学院教学医院 [3]潍坊市中医院,潍坊261042

出　　处：《中国实用神经疾病杂志》2011年第4期5-7,共3页Chinese Journal of Practical Nervous Diseases

摘　　要：目的探讨影响进展性卒中的相关危险因素。方法选取2009-11~2010-10潍坊市中医院中风科住院的72 h内新发脑梗塞患者87例,分为进展性卒中组与非进展性卒中组,观察项目包括：年龄、性别等一般资料的比较,神经功能评分,日常生活能力评分,既往史评分,伴发疾病评分,预后评分及卫生经济学等,对各因素进行单因素分析,然后对有统计学意义的自变量作多因素Logistic回归分析。结果 87例新发脑卒中患者中符合条件的进展性脑卒中患者30例,发生率为34.48%,经单因素分析,其中有7个因素的差异有显著性,包括是否情绪波动史、既往高血压病史、既往糖尿病史、入院当天NIHSS评分、入院当天ADL评分、出院时mRS评分、卫生经济学。以脑卒中是否发生进展为因变量,对经单因素分析有显著意义的自变量作多因素Logistic回归分析,回归显示：既往高血压病史、既往糖尿病史有显著意义,P值分别为0.019,0.006,入院当天NIHSS评分、卫生经济学、入院当天ADL评分、出院mRS评分、是否情绪波动史无显著性差异,即既往有高血压病史、既往有糖尿病史的急性脑卒中患者出现进展的几率高。结论高血压、糖尿病与进展性脑卒中的发生发展密切相关,这些危险因素的研究对防治进展性脑卒中有重要临床意义。Objective To analyze the relative factors that caused stroke in progression（SIP）.Methods We selected 87 cases of cerebral infarction patients who presented within 72 hours of onset from November 2009 to October 2010 in Traditional Chinese Medicine Hospital in Weifang.A total of 87 patients were diagnosed as stroke in progression（SIP） and non progression stroke group（NPS）.Observation items included general information such as age and gender,NIHSS score,ADL score,past medical history score,associated with disease rates,mRS score and health economics.Univariate analysis was carried on the single factors,then we had the statistically significant factors to make multi-factor Logistic regression analysis.Results Of all the 87 cases of cerebral infarction patients,30 cases were divided into SIP,the overall incidence of SIP was 34.48%,seven factors which had significant differences,including the history of mood swings,past history of hypertension,previous history of diabetes,the day of admission NIHSS score,admission day ADL score,mRS score at discharge,health economics.Advances in stroke occurred as the dependent variable,long on Logistic regression analysis,regression showed： Past history of hypertension and previous history of diabetes were statistically significant,P=0.019,0.006.Patients with past history of hypertension and diabetes progress in acute stroke patients had higher risk to becoming SIP.Conclusion Hypertension and diabetes are closely related to SIP.Studying these risk factors is very important to preventing SIP.

关 键 词：进展性脑卒中 高血压 糖尿病 

分 类 号：R743.3[医药卫生—神经病学与精神病学]