颅内肿瘤和睡眠呼吸暂停低通气综合征  

Intracranial tumors and sleep apnea hypopnea syndrome

作　　者：邓晓辉[1,2] 杨波[1] 欧阳松云[3] 张智峰[1] 段小兵[1,2] 乔晓俊[1,2] 张天祥[1,2] 

机构地区：[1]郑州大学第一附属医院神经外科,郑州450052 [2]郑州大学医学院临床医学系,郑州450052 [3]郑州大学第一附属医院睡眠呼吸科,郑州450052

出　　处：《中国实用神经疾病杂志》2011年第5期23-25,共3页Chinese Journal of Practical Nervous Diseases

摘　　要：目的评估颅内肿瘤病人呼吸暂停低通气的类型以及肿瘤切除术在改善呼吸紊乱方面起的作用。方法对30例颅内肿瘤病人(22例幕上,8例幕下)术前、术后进行睡眠呼吸检测。结果术前平均呼吸暂停低通气指数为23.3,18例病人存在阻塞性呼吸暂停,3例病人存在阻塞性和中枢性呼吸暂停。术后平均呼吸暂停低通气指数降为9.6(P<0.05)。结论脑肿瘤病人经常会出现呼吸暂停低通气综合征,这些合并疾病会增加颅内压,从而加重临床症状。肿瘤切除能明显改善呼吸暂停低通气现象。Objective To evaluate the types of sleep apnea hypopnea syndrome before and after operation,and the role of tumorectomy on it.Methods Polysomnographic studies were performed in 30 patients with intracranial tumors（22 supra-and 8 infratentorial） before and after surgery.Results Pre-operatively,the mean apnea-hypopnea index（AHI） was 23.3.Eighteen patients＇ demonstrated signs of obstructive sleep apnea and three had mixed obstructive and central type sleep apnea.After operation,the mean AHI decreased to 9.6（P〈0.05）.Conclusion Patients with brain tumors often suffer from sleep apnea and this can further worsen their symptoms related to increased intracranial pressure.Removal of the tumor results in a substantial decrease in sleep-related disturbances.

关 键 词：颅内肿瘤 睡眠呼吸暂停综合征 呼吸暂停 多导睡眠检测 

分 类 号：R743.73[医药卫生—神经病学与精神病学]