骨盆转移瘤血管内介入治疗的探讨  

Intra arterial Treatment of Pelvic Metastases

作　　者：曾晓华[1] 熊雪峰[2] 郑湖民[1] 王颂章[1] 金德勤[1] 乔英[1] 

机构地区：[1]广州军区武汉总医院放射科,武汉430070 [2]解放军第171医院放射科,江西九江332000

出　　处：《临床放射学杂志》1999年第11期684-687,共4页Journal of Clinical Radiology

摘　　要：目的： 通过１６ 例骨盆转移瘤３１ 人次的髂内、外动脉和／ 或股动脉灌注化疗和栓塞治疗，探讨血管内介入治疗对骨盆转移的治疗效果。材料与方法： 一侧股动脉穿刺插管，髂内、外动脉和／ 或股动脉造影，明确骨盆转移存在及其供血源后，先行动脉内灌注化疗，继以真丝微粒和／ 或明胶海绵碎屑行供血动脉栓塞。栓后即造影观察栓塞程度。治疗后临床上密切观察症状改变，２ ～３ 个月后造影复查，再行动脉内化疗，必要时再行栓塞。结果： 本组１６ 例共行３１ 人次治疗。治疗后局部疼痛减轻和体征改善明显。造影复查示大部原转移灶染色变小、变淡或完全消失，无严重并发症。结论： 血管内灌注化疗并栓塞治疗对骨盆转移是一种有效的姑息治疗手段，尤其对于放疗后不能控制转移或再发转移具有十分重要的治疗价值。Objective: To explore intra arterial treatment of pelvic metastases.Materials and Methods:Angiography of internal iliac artery, external iliac artery and/or femoral artery was performed in 16 cases (31 procedures) with pelvic metastases after catheterization via one femoral artery. Once the tumor feeding arteries were identified, arterial themotherapy was carried out and embolization with silk segments and Gelfoam particles was selectively done. Angiography was repeated to determine the degree of embolization. Clinical symptoms were closely observed. Follow up angiography was done two or three months later, and chemotherapy and embolization were repeated when necessary.Results:Sixteen patients underwent 31 treatment procedures. Pain and other symptoms were markedly relieved in all cases. On follow up angiographies, metastatic lesions became smaller, subtler, or even disappeared.Conclusion: Intra arterial chemotherapy with selective embolization is an effective and palliative treatment for pelvic metastases, especially for those patients who are not suitable for much radiation.

关 键 词：骨盆转移瘤 血管内 介入疗法 

分 类 号：R739.930.5[医药卫生—肿瘤]