Laboratory Detection and Diagnosis of Filoviruses  

作　　者：Yun-peng Wang Xian-en Zhang Hong-ping Wei 

机构地区：[1]State Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan 430071,China

出　　处：《Virologica Sinica》2011年第2期73-80,共8页中国病毒学（英文版）

摘　　要：Ebola virus(EBOV) and Marburg virus(MARV),belonging to the Filoviridae family,emerged four decades ago and caused severe viral hemorrhagic fever in human and other primates.As high as 50-90% mortality,filoviruses can cause significant threats to public health.However,so far no specific and efficient vaccine has been available,nor have other treatment methods proved to be effective.It is of great importance to detect these pathogens specific,rapidly and sensitively in order to control future filovirus outbreaks.Here,recent progresses in the development of detection and diagnosis methods for EBOV and MARV are summarized.Ebola virus （EBOV） and Marburg virus （MARV）, belonging to the Filoviridae family, emerged four decades ago and caused severe viral hemorrhagic fever in human and other primates. As high as 50-90% mortality, filoviruses can cause significant threats to public health. However, so far no specific and efficient vaccine has been available, nor have other treatment methods proved to be effective. It is of great importance to detect these pathogens specific, rapidly and sensitively in order to control future filovirus outbreaks. Here, recent progresses in the development of detection and diagnosis methods for EBOV and MARV are summarized

关 键 词：FILOVIRUS Ebola virus （EBOV） Marburg virus （MARV） Enzyme-linked immunosorbent assay（ELISA） Polymerase chain reaction （PCR） 

分 类 号：S852.659.5[农业科学—基础兽医学] TS251.7[农业科学—兽医学]