脾错构瘤临床病理观察  

Clinicopathologic features of splenic hamartoma

作　　者：姚青[1] 李瑞平[2] 蒋静娟[2] 施中元[1] 赵敏[1] 

机构地区：[1]江苏省中西医结合医院病理科,南京210028 [2]东南大学附属中大医院病理科,南京210009

出　　处：《诊断病理学杂志》2011年第1期38-40,共3页Chinese Journal of Diagnostic Pathology

摘　　要：目的探讨脾错构瘤的临床病理特征、免疫表型及鉴别诊断。方法报道1例脾错构瘤的临床病理和免疫组化,结合文献对该肿瘤的临床病理学特征、诊断与鉴别诊断进行讨论。结果脾错构瘤常偶然发现。肿块境界清,由随意排列的血管腔隙构成,腔内衬窦内皮细胞,宽的髓索样间隔中富于网状纤维,散在间质细胞、淋巴细胞和嗜酸性粒细胞浸润。免疫组化示CD31(+),CD34(-)/CD8(+)。结论脾错构瘤为罕见的良性肿瘤,明确诊断须结合临床、组织学及免疫组化标记。Objective To explore the clinicopathological features,immunohistochemical profile and differential diagnosis of splenic hamartoma.Methods A case of splenic hamartoma was investigated with histopathological and immunohistochemical stains.Relevant literatures were reviewed.Results Splenic hamartoma most commonly represented an incidental finding.It formed a discrete nodule and consisted of haphazardly disposed vascular channels lined by splenic sinus endothelium and separated by wide pulp cord-like elements with intervning network of reticulin.There was variable numbers of inventing cells,lymphocytes and eosinophils in the stroma.Conclusion Splenic hamartoma is a rare benign tumour.Rendering a diagnosis should be based on clinical,histologic and immunopathologic correlation.

关 键 词：脾 错构瘤 免疫组化标记 

分 类 号：R733.2[医药卫生—肿瘤]