肺硬化性血管瘤的临床特点及外科治疗  

Clinical characteristics and surgical treatment of pulmonary sclerosing hemangioma

作　　者：房建伟[1] 刘凡英[1] 李军[1,2] 

机构地区：[1]山东大学附属省立医院胸外科,济南250021 [2]江西省肿瘤医院胸外科,南昌330029

出　　处：《山东大学学报（医学版）》2011年第2期83-87,共5页Journal of Shandong University:Health Sciences

基　　金：江西省科技支撑计划重点项目(2009BGA11700);江西省自然科学基金资助项目(2009GZY0086;2010GZY0132)

摘　　要：目的探讨肺硬化性血管瘤临床表现特点、诊断及治疗,提高对本病的认识。方法对18例肺硬化性血管瘤病例临床资料回顾性分析,并复习相关文献。结果 18例均石蜡病理切片确诊为肺硬化性血管瘤,男2例,女16例。发病年龄18~56岁,平均41.6岁。12例系体检发现,6例因各种症状就诊,其中咳嗽4例,咳嗽并胸痛1例,痰中带血1例。影像学多表现为肺周边单个孤立的圆形或类圆形结节,边界清楚,密度均匀,部分点状钙化。18例均手术治疗,8例肺叶切除,1例肺楔形切除,9例肿瘤摘除。无手术并发症及手术死亡。随访期间患者无肿瘤复发及转移。结论肺硬化性血管瘤临床及影像学检查缺乏特异性,确诊需外科病理检查。中年女性,出现肺部周边孤立、边界清楚、密度均匀的圆或椭圆形结节,无论有或无临床症状,应考虑到此病,并积极手术治疗。Objective：To investigate the clinical characteristics,diagnosis and treatment of pulmonary sclerosing hemangioma（PSH） and to deepen the understanding of PSH.Methods：Clinical data from 18 patients with PSH,who underwent surgical resection in the Provincial Hospital Affiliated to Shandong University from April 2004 to March 2010,and the related literature were retrospectively reviewed.Results：Of the 18 patients with PSH confirmed by histopathology,2 were males and 16 were females.The median age was 41.6 years,ranging from 18 to 56 years.12 patients were detected by physical examination,while 4 patients presented with cough,1 with cough and chest pain,and 1 with blood-stained sputum.The imaging examination generally revealed the peripherally solitary,well-circumscribed,and round or similarly round nodule with homogeneous density,and partly punctiform calcification.All these 18 patients received surgical resection without complications and mortality,8 with lobectomy,1 with wedge resection and 9 with tumor enucleation.No recurrence and no metastasis were detected during follow-ups.Conclusions：Clinical characteristics and imaging examinations of PSH are lack of specificity,and the accurate diagnosis depends on pathological examination.PSH should be suspected in middle-aged female patients with a peripherally solitary,well-circumscribed,and round or similarly round nodule of homogeneous density,whether the patients present symptoms or not.Surgical resection is effective for PSH.

关 键 词：肺肿瘤 硬化性血管瘤 诊断 手术治疗 

分 类 号：R734.2[医药卫生—肿瘤] R655.3[医药卫生—临床医学]