影响子宫颈癌预后的高危因素分析  

Analysis of high risk factor for prognosis of cervical cancer

作　　者：杨越波[1] 曾海涛[1] 唐虹[2] 

机构地区：[1]中山大学附属第三医院妇科,广东广州510630 [2]广东省中医院妇科

出　　处：《中国妇幼保健》2011年第8期1145-1148,共4页Maternal and Child Health Care of China

摘　　要：目的:回顾性分析总结影响子宫颈癌预后的高危因素。方法:对2003年1月～2008年12月间中山大学附属第三医院妇科收治的116例子宫颈癌病例进行回顾性分析,进一步探讨病理类型、组织学分级、肌层浸润深度、淋巴结转移、临床分期与预后之间的关系。结果:临床分期(P=0.022)、病理类型(P=0.003)、组织学分级(P=0.000)、盆腔淋巴结转移(P=0.008)与宫颈癌预后显著相关;年龄(P=0.236)、肿瘤直径(≤4 cm vs>4 cm)(P=0.491)、宫颈肌层浸润深度(P=0.270)与预后无显著相关。COX回归多因素分析,临床分期、组织学分级对生存时间的影响差异有统计学意义(P<0.05)。结论:病理类型、组织学低分化、淋巴结转移、期别晚是提示预后不良的高危因素。Objective：To analyze the high risk factor for prognosis of cervical cancer. Methods：To summarize the influence of pathologic type,histological grade,myometrial invasion depth,lymph node metastasis,surgical-pathologic stage and complications on prognosis of 116 cases with cervical cancer in the Third Affiliated Hospital of Sun Yat-Sen University from Jan.2003 to Dec.2008. Results：Clinical stages（P=0.022）,pathologic types（P=0.003）,histological grade（P=0.000）,lymph node metastasis（P=0.008） were statistically significant factors of prognosis.Age（P=0.236）,tumor diameter（P=0.491） and depth of myometrial invasion（P=0.270） were not statistically significant factors of prognosis.By multivariate analysis,clinical stages and histological grade were independent high risk factors for prognosis（P0.05）. Conclusion：Pathologic types,low histological grade,lymph node metastasis,late-stages are high risk factors of prognosis.

关 键 词：子宫颈癌 高危因素 预后 

分 类 号：R737.33[医药卫生—肿瘤]