降钙素原和乳酸测定对老年脓毒症患者预后判断的意义  

The role of evaluating procalcitonin(PCT) and lactic acid for predicting the outcome of elderly patients with sepsis

作　　者：黄增相[1] 杨兴易[2] 

机构地区：[1]上海市普陀区人民医院急诊科,上海200060 [2]上海长征医院急救科

出　　处：《临床医学》2011年第3期23-24,共2页Clinical Medicine

摘　　要：目的通过监测急诊ICU老年脓毒症患者降钙素原(PCT)、乳酸水平等指标以评价PCT和乳酸水平对老年脓毒症患者预后判断的意义。方法选择82例老年脓毒症患者,分别检测入住ICU后24 h内的降钙素原、乳酸和C-反应蛋白水平,从患者入住急诊ICU作为研究起点,患者出院或死亡作为研究的终点;其中死亡30例,存活52例。结果死亡组的PCT浓度、动脉血乳酸浓度明显高于存活组(P<0.001),而C-反应蛋白浓度在生存组和死亡组间比较差异无统计学意义(P>0.05)。结论血清降钙素原和血乳酸的水平检测,对老年脓毒症患者严重程度及其预后的判定有一定的指导意义,可应用于临床。Objective To evaluate the role of procalcitonin（PCT） and lactic acid for predicting the outcome of elderly patients with sepsis in emergency ICU.Methods Eighty-two patients suffered from sepsis were enrolled in this study.Procalcitonin,lactic acid and C-reactive protein values were detected within 24 hours after ICU admission.Patients admitted to the emergency ICU as a research starting point,the patients discharge or death as the end of the study.Fifty-two cases survived and 30 cases died.Results PCT and blood lactate concentration in the death group was significantly higher than that in the survival group（P0.001）.C-reactive protein concentration in the death group showed no significant difference compared with that in the survival group.Conclusion Serum procalcitonin and blood lactate testing in elderly patients with sepsis could help to determine the severity and prognosis of the patients.

关 键 词：老年 脓毒症 降钙素原 乳酸 预后 

分 类 号：R459.7[医药卫生—急诊医学]